TDIQ (hydrochloride)

TDIQ (hydrochloride) is an analytical reference standard that is classified as a phenylalkylamine. It is related in structure to amphetamines but does not appear to affect locomotor activity. TDIQ is a partial agonist of alpha2A-, alpha2B-, and alpha2C-adrenergic receptors (Kis = 75, 95, and 65 nM, respectively) but has low affinity for dopamine or serotonin receptors and does not affect catecholamine release in rodent brain synaptosomes. Drug discrimination studies in rats indicate that it can serve as a discriminative stimulus, generalizing to cocaine (Cay-16186, ISO60176) and partially to 3,4-MDMA (Cay-13971, ISO60190) and methcathinone (Cay-11709), but not to amphetamine (Cay-15797, 15650). TDIQ has also been shown to exhibit anxiolytic and anorectic effects in rodent models. This product is intended for forensic and research purposes.Formal Name: 5,6,7,8-tetrahydro-1,3-dioxolo[4,5-g]isoquinoline, monohydrochloride. CAS Number: 15052-05-8. Molecular Formula: C10H11NO2 . HCl. Formula Weight: 213.7. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 14 mg/ml, DMSO: 20 mg/ml, Ethanol: 0.3 mg/ml, PBS (pH 7.2): 5 mg/ml. lambdamax: 235, 292 nm. SMILES: C1(CCNC2)=C2C=C(OCO3)C3=C1.Cl. InChi Code: InChI=1S/C10H11NO2.ClH/c1-2-11-5-8-4-10-9(3-7(1)8)12-6-13-10,/h3-4,11H,1-2,5-6H2,1H. InChi Key: DOJLHSBHORQYDE-UHFFFAOYSA-N.