JWH 073 4-hydroxyindole metabolite-d7

JWH 073 4-hydroxyindole metabolite-d7 contains seven deuterium atoms at the 2, 2', 3, 3', 4, 4, and 4 positions. It is intended for use as an internal standard for the quantification of JWH 073 4-hydroxyindole metabolite by GC- or LC-mass spectrometry (MS). JWH 073 is a mildly selective agonist of the central cannabinoid (CB1) receptor derived from the aminoalkylindole WIN 55,212-2. The Ki values for binding CB1 and the peripheral cannabinoid (CB2) receptor are 8.9 and 38 nM, respectively for a CB1:CB2 ratio of 0.23. JWH 073 is one of several synthetic CBs which have been included in smoking mixtures. JWH 073 4-hydroxyindole metabolite is expected to be a urinary metabolite of JWH 073 based on the metabolism of the closely-related JWH 015 and JWH 018.Formal Name: (1-butyl-(2,2,3,3,4,4,4-d7)-4-hydroxy-1H-indol-3-yl)(naphthalen-1-yl)-methanone. Molecular Formula: C23H14D7NO2. Formula Weight: 350.5. Purity: >99% deuterated forms (d1-d7). Formulation: (Request formulation change), A solution in methanol. Solubility: DMF: 20 mg/ml, DMSO: 20 mg/ml, Ethanol: 20 mg/ml. lambdamax: 218, 355 nm. SMILES: [2H]C(C(C([2H])([2H])[2H])([2H])[2H])([2H])CN1C2=CC=CC(O)=C2C(C(C3=CC=CC4=C3C=CC=C4)=O)=C1. InChi Code: InChI=1S/C23H21NO2/c1-2-3-14-24-15-19(22-20(24)12-7-13-21(22)25)23(26)18-11-6-9-16-8-4-5-10-17(16)18/h4-13,15,25H,2-3,14H2,1H3/i1D3,2D2,3D2. InChi Key: DKIVMJXJKHHIRO-NCKGIQLSSA-N.