Clenbuterol-d9

Clenbuterol-d9 is intended for use as an internal standard for the quantification of clenbuterol (Cay-14985) by GC- or LC-MS. Clenbuterol is an agonist of beta2-adrenergic receptors (beta2-ARs). It induces relaxation of equine tracheal muscle strips (EC50 = 2.1 nM). Clenbuterol (300 nM) increases the number of autophagosomes and autophagic flux in HepG2 cells. It increases blood flow to adipose tissue and induces weight gain in rats when administered at a dose of 2 mg/kg, as well as induces relaxation of bovine uterus. Clenbuterol also inhibits infection of MDCK cells by an H1N1 influenza isolate in vitro (EC50 = 9.4 µM). Formulations containing clenbuterol have been used in the treatment of airway obstruction in horses.Formal Name: 4-amino-3,5-dichloro-alpha-[[[1,1-di(methyl-d3)ethyl-2,2,2-d3]amino]methyl]-benzenemethanol. CAS Number: 129138-58-5. Synonyms: NAB 365-d9. Molecular Formula: C12H9Cl2D9N2O. Formula Weight: 286.2. Purity: >99% deuterated forms (d1-d9). Formulation: (Request formulation change), A solid. Solubility: DMSO: Slightly soluble, Methanol: Slightly soluble. SMILES: [2H]C([2H])([2H])C(C([2H])([2H])[2H])(C([2H])([2H])[2H])NCC(C1=CC(Cl)=C(C(Cl)=C1)N)O. InChi Code: InChI=1S/C12H18Cl2N2O/c1-12(2,3)16-6-10(17)7-4-8(13)11(15)9(14)5-7/h4-5,10,16-17H,6,15H2,1-3H3/i1D3,2D3,3D3. InChi Key: STJMRWALKKWQGH-GQALSZNTSA-N.