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Zu "K04142" wurden 146 Artikel gefunden!
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NEU
Artikelnummer: Cay40816-1
Clenbuterol-d9 is intended for use as an internal standard for the quantification of clenbuterol (Cay-14985) by GC- or LC-MS. Clenbuterol is an agonist of beta2-adrenergic receptors (beta2-ARs). It induces relaxation of equine tracheal muscle strips (EC50 = 2.1 nM). Clenbuterol (300 nM) increases the number of...
Schlagworte: | NAB 365-d9, 4-amino-3,5-dichloro-alpha-[[[1,1-di(methyl-d3)ethyl-2,2,2-d3]amino]methyl]-benzenemethanol |
Anwendung: | GC-MS, LC-MS internal standard, quantification, beta2-adrenergic receptor agonist |
CAS | 129138-58-5 |
MW: | 286.2 D |
ab 267,00 €
Artikelnummer: Cay39536-10
Vilanterol is a long-acting agonist of the beta2-adrenergic receptor (beta2-AR). It selectively induces cAMP accumulation in CHO cells expressing the beta2-AR over the beta1- and beta3-ARs (EC50s = 0.4, 398, and 794 nM for the human receptors, respectively). Vilanterol inhibits contractions induced by electrical...
Schlagworte: | GW 642444M, alpha1R-[[[6-[2-[(2,6-dichlorophenyl)methoxy]ethoxy]hexyl]amino]methyl]-4-hydroxy-1,3-benzenedimethanol,... |
Anwendung: | Beta2-AR agonist |
CAS | 503070-58-4 |
MW: | 774.8 D |
ab 66,00 €
Artikelnummer: IB-IB32101
This is an all-inclusive cell-based luciferase reporter assay kit targeting the the Human Adrenoreceptor Beta 2 (ADRB2). INDIGO's ADRB1 reporter assay utilizes proprietary mammalian cells that have been engineered to provide constitutive expression of the ADRB2. In addition to ADRB2 Reporter Cells, this kit provides...
Schlagworte: | ADRB2, ADRB2R, Beta-2 adrenoceptor, Beta-2 adrenoreceptor, Beta-2 adrenergic receptor |
Anwendung: | Functional activity screening |
Spezies-Reaktivität: | human |
1.448,00 €
Artikelnummer: IB-IB32102
This is an all-inclusive cell-based luciferase reporter assay kit targeting the the Human Adrenoreceptor Beta 2 (ADRB2). INDIGO's ADRB1 reporter assay utilizes proprietary mammalian cells that have been engineered to provide constitutive expression of the ADRB2. In addition to ADRB2 Reporter Cells, this kit provides...
Schlagworte: | ADRB2, ADRB2R, Beta-2 adrenoceptor, Beta-2 adrenoreceptor, Beta-2 adrenergic receptor |
Anwendung: | Functional activity screening |
Spezies-Reaktivität: | human |
3.803,00 €
Artikelnummer: ELK-ELK6738.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse ADRb2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse ADRb2. Next,...
Schlagworte: | Adrb2, Adrb2r, Beta-2 adrenoceptor, Beta-2 adrenoreceptor, Beta-2 adrenergic receptor |
Anwendung: | ELISA |
Spezies-Reaktivität: | mouse |
ab 365,00 €
Artikelnummer: Cay15591-10
ICI 118551 is a potent, selective antagonist of the beta2-adrenergic receptor (Ki = 0.7 nM for the beta2 receptor, compared with 49.5 and 611 nM for beta1 and beta3 receptors, respectively). It is active in vivo and is often used to evaluate the actions of adrenergic receptor agonists.Formal Name:...
Schlagworte: | (2R,3R)-rel-1-[(2,3-dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-2-butanol, monohydrochloride |
Anwendung: | beta2-adrenergic receptor antagonist |
CAS | 72795-01-8 |
MW: | 313.9 D |
ab 195,00 €
Artikelnummer: Cay21245-1
(±)-Epinephrine is a natural neurotransmitter that is released from the adrenal medulla and activates adrenoceptors (Kis = 15, 735, and 3,970 nM for alpha1A-, beta2-, and beta1-adrenergic receptors, respectively). Through these receptors, (±)-epinephrine may induce either contraction or relaxation of vascular smooth...
Schlagworte: | (±)-Adrenaline, DL-Adrenaline, DL-Epinephrine, 4-[1-hydroxy-2-(methylamino)ethyl]-1,2-benzenediol, monohydrochloride |
Anwendung: | Natural neurotransmitter, Adrenoceptor activator |
CAS | 329-63-5 |
MW: | 219.7 D |
44,00 €
Artikelnummer: Cay21794-1
Olodaterol is a selective agonist of beta2-adrenergic receptors (beta2-ARs, EC50s = 97.7 and 2,725 nM for human beta2- and beta1-ARs, respectively). In vivo, olodaterol completely reverses acetylcholine-induced bronchoconstriction without cardiovascular side effects in guinea pigs. It also exhibits dose-dependent...
Schlagworte: | BI-1744, 6-hydroxy-8-[(1R)-1-hydroxy-2-[[2-(4-methoxyphenyl)-1,1-dimethylethyl]amino]ethyl]-2H-1,4-benzoxazin-3(4H)-one |
Anwendung: | beta2-Adrenergic receptor agonist |
CAS | 868049-49-4 |
MW: | 386.4 D |
ab 113,00 €
Artikelnummer: Cay15584-10
Formoterol is a selective agonist of the beta2-adrenergic receptor (beta2-AR, Kis = 7.58 and 2,630 nM for beta2- and beta1-ARs, respectively). It is selective for beta-ARs in isolated guinea pig trachea over those in atrial tissue (pD2s = 9.29 and 6.98, respectively) and has a long duration of action. Aerosolized...
Schlagworte: | rel-N-[2-hydroxy-5-[(1R)-1-hydroxy-2-[[(1R)-2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]-formamide,... |
Anwendung: | beta2-adrenergic receptor agonist |
MW: | 402.5 D |
ab 130,00 €
Artikelnummer: Cay20070-50
Indacaterol is a long-acting and selective beta2-adrenergic receptor (beta2-AR) agonist (EC50 = 8.71 nM for increasing intracellular cAMP levels in vitro). It is selective for beta2-ARs over beta1- and beta3-ARs (Kis = 43.6, 616.6, and 3,311.3 nM, respectively). Indacaterol inhibits bronchoconstriction induced by...
Schlagworte: | QAB149, 5-[(1R )-2-[(5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-hydroxy 2(1H )-quinolinone |
Anwendung: | beta2-Adrenergic receptor agonist |
CAS | 312753-06-3 |
MW: | 392.5 D |
ab 66,00 €
Artikelnummer: Cay16009-10
Salmeterol is a long-acting beta2-adrenergic receptor agonist (beta2-AR, EC50s = 0.79, 63.1, and 9.4 nM for beta2-, beta1-, and beta3-ARs, respectively). It inhibits electrically-stimulated contraction of isolated guinea pig trachea strips (EC50 = 2.51 nM) and histamine-induced bronchoconstriction in guinea pigs via...
Schlagworte: | GR-33343G, 4-hydroxy-alpha1-[[[6-(4-phenylbutoxy)hexyl]amino]methyl]-1,3-benzenedimethanol,... |
Anwendung: | beta2-adrenergic receptor agonist |
CAS | 94749-08-3 |
MW: | 603.8 D |
ab 147,00 €
Artikelnummer: Cay16136-100
Sotalol is a non-selective antagonist of beta-adrenergic receptors (beta-ARs, IC50s = 8.9 and 5.2 µM for beta1- and beta2-ARs, respectively) and a class III antiarrhythmic agent. It decreases delayed outward potassium currents (IK) in guinea pig ventricular cells and prolongs action potential duration in...
Schlagworte: | (±)-Sotalol, DL-Sotalol, MJ1999, N-[4-[1-hydroxy-2-[(1-methylethyl)amino]ethyl]phenyl]-methanesulfonamide, monohydrochloride |
Anwendung: | beta1/2-adrenergic receptor antagonist |
CAS | 959-24-0 |
MW: | 308.8 D |
ab 43,00 €