Icaritin

Icaritin is a flavonoid first isolated from the Chinese herb H. epimedii that demonstrates anticancer activity against a variety of tumor cell lines. It has been shown to inhibit fatty acid synthase, reducing IGF-1-induced activation of STAT3 in several melanoma cell lines.Formal Name: 3,5,7-trihydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one. CAS Number: 118525-40-9. Molecular Formula: C21H20O6. Formula Weight: 368.4. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 3 mg/mL, DMSO: 5 mg/mL, DMSO:PBS (pH 7.2)(1:5): 0.16 mg/mL, Ethanol: 0.3 mg/mL. lambdamax: 273, 318, 374 nm. SMILES: C/C(C)=C\CC1=C2C(C(C(O)=C(C3=CC=C(OC)C=C3)O2)=O)=C(O)C=C1O. InChi Code: InChI=1S/C21H20O6/c1-11(2)4-9-14-15(22)10-16(23)17-18(24)19(25)20(27-21(14)17)12-5-7-13(26-3)8-6-12/h4-8,10,22-23,25H,9H2,1-3H3. InChi Key: TUUXBSASAQJECY-UHFFFAOYSA-N.