Zu "K00665" wurden 87 Artikel gefunden!
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Anti-Recombinant FASN, clone A219
Artikelnummer: E-AN301520L.100
Fatty acid synthetase is a multifunctional enzyme that catalyzes the de novo biosynthesis of long-chain saturated fatty acids starting from acetyl-CoA and malonyl-CoA in the presence of NADPH. This multifunctional protein contains 7 catalytic activities and a site for the binding of the prosthetic group...
| Schlagworte: | Anti-FASN, Anti-Fatty acid synthase, Anti-Type I fatty acid synthase, Recombinant FASN Monoclonal Antibody |
| Anwendung: | WB, IHC, FCM, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat, mouse |
ab 304,00 €
Anti-Recombinant Fatty Acid Synthase, clone 2D7
Artikelnummer: E-AN300835L.100
The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha...
| Schlagworte: | Anti-FASN, Anti-Fatty acid synthase, Anti-Type I fatty acid synthase, Recombinant Fatty Acid Synthase Monoclonal Antibody |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 258,00 €
Malonyl Coenzyme A (lithium salt)
Artikelnummer: Cay16455-5
Malonyl coenzyme A is a coenzyme A (CoA, Cay-16147) derivative that is used in fatty acid and polyketide synthesis and in the transport of alpha-ketoglutarate across the mitochondrial membrane. Malonyl-CoA is formed by acetyl-CoA carboxylase-mediated carboxylation of acetyl-CoA (Cay-16160). Fatty acid synthase...
| Schlagworte: | Malonyl-CoA, S-(hydrogen propanedioate) coenzyme A, lithium salt |
| Anwendung: | Fatty acid & polyketide synthesis intermediate |
| CAS | 108347-84-8 |
| MW: | 860.5 D |
ab 73,00 €
GSK2194069
Artikelnummer: Cay20022-5
GSK2194069 is an inhibitor of fatty acid synthase (FASN) with an IC50 value of 7.7 nM in an assay detecting released CoA. It is a competitive inhibitor that is selective for the KR domain over the KS domain of FASN, with IC50 values of 29 and >10,000 nM, respectively, in vitro. GSK2194069 decreases incorporation of...
| Schlagworte: | 4-[4-(5-benzofuranyl)phenyl]-5-[[(3S)-1-(cyclopropylcarbonyl)-3-pyrrolidinyl]methyl]-2,4-dihydro-3H-1,2,4-triazol-3-one |
| Anwendung: | FASN inhibitor |
| CAS | 1332331-08-4 |
| MW: | 428.5 D |
ab 49,00 €
Anti-FASN
Artikelnummer: A301-323A
Protein function: Fatty acid synthetase catalyzes the formation of long- chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities and an acyl carrier protein. [The UniProt Consortium]
| Schlagworte: | Anti-FAS, Anti-FASN, EC=2.3.1.85, EC=2.3.1.38, EC=2.3.1.41, EC=3.1.2.14, EC=2.3.1.39, EC=4.2.1.59, EC=1.3.1.39,... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
TVB-2640
Artikelnummer: Cay35703-1
TVB-2640 is an inhibitor of fatty acid synthase (FASN, IC50 = 0.5 µM). It inhibits infection of an infectious-clone-derived severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) reporter virus in HEK293T cells expressing human angiotensin-converting enzyme 2 (ACE2, EC50 = 4 nM).Formal Name:...
| Schlagworte: | Denifanstat, FASN-IN-2, Fatty Acid Synthase Inhibitor 2,... |
| Anwendung: | FASN inhibitor |
| CAS | 1399177-37-7 |
| MW: | 439.6 D |
ab 84,00 €
(+)-trans-C75
Artikelnummer: Cay9000783-1
C75 is stable fatty acid synthase (FASN) inhibitor that when administered in racemic form leads to profound weight loss and feeding inhibition in both high-fat diet wild type obese and leptin-deficient ob/ob mice. C75 is also cytotoxic to many human cancer cell lines, an effect believed to be mediated by the...
| Schlagworte: | (2R,3S)-C75, tetrahydro-4-methylene-2S-octyl-5-oxo-3R-furancarboxylic acid |
| Anwendung: | FAS inhibitor |
| CAS | 1234694-20-2 |
| MW: | 254.3 D |
ab 255,00 €
UCM05
Artikelnummer: Cay19090-5
UCM05 is an inhibitor of fatty acid synthase that strongly suppresses the growth of human breast cancer cell lines (IC50 = 21 µM for SK-BR-3 cells). It does not alter carnitine palmitoyltransferase 1 activity or induce weight loss in mice. UCM05 can reduce cleavage of poly(ADP-ribose) polymerase, phosphorylation of...
| Schlagworte: | G28UCM, 3,4,5-trihydr3,4,5-trihydroxy-benzoic acid 1,1'-(1,3-naphthalenediyl) ester |
| Anwendung: | Fatty acid synthase inhibitor |
| CAS | 1094451-90-7 |
| MW: | 464.4 D |
ab 49,00 €
Anti-FASN
Artikelnummer: A301-324A-T
Protein function: Fatty acid synthetase catalyzes the formation of long- chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities and an acyl carrier protein. [The UniProt Consortium]
| Schlagworte: | Anti-FAS, Anti-FASN, EC=2.3.1.85, EC=2.3.1.38, EC=2.3.1.41, EC=3.1.2.14, EC=2.3.1.39, EC=4.2.1.59, EC=1.3.1.39,... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 165,00 €
Icaritin
Artikelnummer: Cay20236-5
Icaritin is a flavonoid first isolated from the Chinese herb H. epimedii that demonstrates anticancer activity against a variety of tumor cell lines. It has been shown to inhibit fatty acid synthase, reducing IGF-1-induced activation of STAT3 in several melanoma cell lines.Formal Name:...
| Schlagworte: | 3,5,7-trihydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one |
| Anwendung: | Anticancer agent, fatty acid synthase inhibitor |
| CAS | 118525-40-9 |
| MW: | 368.4 D |
ab 49,00 €
TVB-3166
Artikelnummer: Cay33533-1
TVB-3166 is an inhibitor of fatty acid synthase (FASN, IC50 = 0.042 µM). It inhibits the biosynthesis of palmitate (Cay-10010279) in Calu-6 non-small cell lung cancer (NSCLC) cells and MRC-5 lung fibroblasts in a concentration-dependent manner. TVB-3166 (0.2 µM) induces apoptosis in Calu-6, as well as 22Rv1 prostate...
| Schlagworte: | 4-[1-[5-(4,5-dimethyl-1H-pyrazol-3-yl)-2,4-dimethylbenzoyl]-3-azetidinyl]-benzonitrile |
| Anwendung: | FASN inhibitor |
| CAS | 1533438-83-3 |
| MW: | 384.5 D |
ab 52,00 €
DPVP (Resveratrol Analog)
Artikelnummer: AG-CR1-3604-M001
White to off-white powder. Soluble in DMSO or methanol. Insoluble in water. Anticancer compound. Shown to inhibit progression of prostate cancer cells, Anti-obesity agent, 3T3-L1 adipocyte differentiation and FASN expression inhibitor.
| Schlagworte: | Resveratrol Analog I, 4-[2-(3,5-Dimethoxyphenyl)-vinyl]pyridine |
| Anwendung: | Anticancer compound, Antiobesity agent, 3T3-L1 adipocyte differentiation / FASN expression inhibitor |
| CAS | 223386-36-5 |
| MW: | 241,3 D |
154,00 €