8-iso Prostaglandin A1

8-iso Prostaglandin A1 (8-iso PGA1) is an isoprostane. It inhibits aldo-keto reductase family 1 member B10 (AKR1B10) in COS-7 lysates expressing the human enzyme when used at a concentration of 60 µM. 8-iso PGA1 (0.1 µM) inhibits potassium-induced D-aspartate release from isolated bovine retinas.Formal Name: (8beta)-15S-hydroxy-9-oxo-prosta-10,13E-dien-1-oic acid. CAS Number: 211186-29-7. Synonyms: 8-epi PGA1, 8-iso PGA1. Molecular Formula: C20H32O4. Formula Weight: 336.5. Purity: >97%. Formulation: (Request formulation change), A solution in methyl acetate. Solubility: DMF: 75 mg/ml, DMSO: 50 mg/ml, Ethanol: 100 mg/ml, PBS pH 7.2: 2.4 mg/ml. lambdamax: 217 nm. SMILES: O=C1[C@@H](CCCCCCC(O)=O)[C@@H](/C=C/[C@@H](O)CCCCC)C=C1. InChi Code: InChI=1S/C20H32O4/c1-2-3-6-9-17(21)14-12-16-13-15-19(22)18(16)10-7-4-5-8-11-20(23)24/h12-18,21H,2-11H2,1H3,(H,23,24)/b14-12+/t16-,17-,18-/m0/s1. InChi Key: BGKHCLZFGPIKKU-DRSVPBQLSA-N.