Pyroxamide

Pyroxamide is an inhibitor of histone deacetylases (HDACs), including HDAC1 (IC50 = 0.1-0.2 µM). It induces growth suppression and cell death of certain types of cancer cells in culture.Formal Name: N1-hydroxy-N8-3-pyridinyl-octanediamide. CAS Number: 382180-17-8. Molecular Formula: C13H19N3O3. Formula Weight: 265.3. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 2 mg/ml, DMSO: 5 mg/ml, DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml. lambdamax: 203, 241, 279 nm. SMILES: O=C(CCCCCCC(NO)=O)NC1=CC=CN=C1. InChi Code: InChI=1S/C13H19N3O3/c17-12(15-11-6-5-9-14-10-11)7-3-1-2-4-8-13(18)16-19/h5-6,9-10,19H,1-4,7-8H2,(H,15,17)(H,16,18). InChi Key: PTJGLFIIZFVFJV-UHFFFAOYSA-N.