Zu "K06067" wurden 267 Artikel gefunden!
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SAHA
Artikelnummer: Cay10009929-100
SAHA is a histone deacetylase (HDAC) inhibitor that binds directly to the catalytic site of the enzyme thereby blocking substrate access. It inhibits class I, II, and IV HDACs at 50-200 nM and arrests cell growth in a wide variety of transformed cells in culture at 2.5-5.0 µM.Formal Name:...
| Schlagworte: | Suberoylanilide Hydroxamic Acid, Vorinostat, N1-hydroxy-N8-phenyl-octanediamide |
| Anwendung: | HDAC inhibitor |
| CAS | 149647-78-9 |
| MW: | 264.3 D |
ab 34,00 €
HDAC-1, active human recombinant protein
Artikelnummer: BPS-50051
Active human HDAC1, GenBank Accession No. NM_004964, full length with C-terminal HIS-DDDDK tag (FLAG), MW= 56 kDa, expressed in baculovirus expression system.
| Schlagworte: | HD1, Histone deacetylase 1, Protein deacetylase HDAC1, Protein decrotonylase HDAC1, |
| Anwendung: | Enzyme kinetics, inhibitor screening |
| MW: | 56 kD |
716,00 €
Valproic Acid-d4
Artikelnummer: Cay39966-1
Valproic acid-d4 is intended for use as an internal standard for the quantification of valproic acid (Cay-35739, Cay-13033) by GC- or LC-MS. Valproic acid is an analog of the natural fatty acid valeric acid that inhibits class I histone deacetylases (HDACs) with IC50 values of approximately 2 mM. It decreases the...
| Schlagworte: | 2-Propylvaleric Acid-d4, Valproate-d4, VPA-d4, 2-(propyl-1,1-d2)-pentanoic-3,3-d2 acid |
| Anwendung: | GC-MS, LC-MS internal standard, quantification, class I HDAC inhibitor |
| CAS | 87745-17-3 |
| MW: | 148.2 D |
ab 133,00 €
Trichostatin A
Artikelnummer: Cay89730-1
Trichostatin A is a potent, reversible inhibitor of class I, II, and IV histone deacetylases (HDACs). In human Jurkat T cells, trichostatin A arrests cell cycle progression in G1 and inhibits the activity of HDAC1 with an IC50 value of 70 nM. Trichostatin A selectively inhibits the removal of acetyl groups from the...
| Schlagworte: | TSA, 7-[4-(dimethylamino)phenyl]-N-hydroxy-4,6R-dimethyl-7-oxo-2E,4E-heptadienamide |
| Anwendung: | HDAC inhibitor |
| CAS | 58880-19-6 |
| MW: | 302.4 D |
ab 76,00 €
Mouse HDAC2 (Histone Deacetylase 2) ELISA Kit
Artikelnummer: ELK-ELK6403.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse HDAC2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse HDAC2. Next,...
| Schlagworte: | HD2, Yy1bp, Histone deacetylase 2, Protein deacylase HDAC2, YY1 transcription factor-binding protein |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
ab 365,00 €
Rat HDAC1 (Histone Deacetylase 1) ELISA Kit
Artikelnummer: ELK-ELK6795.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat HDAC1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat HDAC1. Next,...
| Schlagworte: | HD1, Hdac1, Histone deacetylase 1, Protein deacetylase HDAC1, Protein decrotonylase HDAC1 |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | rat |
ab 365,00 €
Human HDAC2 (Histone Deacetylase 2) ELISA Kit
Artikelnummer: ELK-ELK2958.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human HDAC2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human HDAC2. Next,...
| Schlagworte: | HD2, Histone deacetylase 2, Protein deacylase HDAC2 |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
Human HDAC1 (Histone Deacetylase 1) ELISA Kit
Artikelnummer: ELK-ELK4042.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human HDAC1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human HDAC1. Next,...
| Schlagworte: | HD1, Histone deacetylase 1, Protein deacetylase HDAC1, Protein decrotonylase HDAC1 |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
Mouse HDAC1 (Histone Deacetylase 1) ELISA Kit
Artikelnummer: ELK-ELK6908.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse HDAC1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse HDAC1. Next,...
| Schlagworte: | HD1, Histone deacetylase 1, Protein deacetylase HDAC1, Protein decrotonylase HDAC1 |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
ab 365,00 €
Valproic Acid (sodium salt)
Artikelnummer: Cay13033-10
Valproic acid is an analog of the natural fatty acid valeric acid that inhibits class I histone deacetylases (HDACs) with an IC50 value of approximately 2 mM. It decreases the number of axon branches in sensory neurons isolated from newborn rat dorsal root ganglia, an effect that is reversed by...
| Schlagworte: | 2-Propylvaleric Acid, Valproate, VPA, 2-propyl-pentanoic acid, monosodium salt |
| Anwendung: | HDAC inhibitor |
| CAS | 1069-66-5 |
| MW: | 166.2 D |
ab 50,00 €
Sodium 4-Phenylbutyrate
Artikelnummer: Cay11323-1
Sodium 4-phenylbutyrate is a chemical chaperone that has been shown to rescue the trafficking of misfolded proteins. It also weakly blocks histone deacetylase activity (IC50 = 0.4 mM), which results in cell cycle arrest, differentiation, and/or apoptosis of various tumors. Formulations containing sodium...
| Schlagworte: | Benzenebutanoic Acid, NSC 657802, TriButyrate, benzenebutanoic acid, monosodium salt |
| Anwendung: | Chemical chaperone, HDAC inhibitor |
| CAS | 1716-12-7 |
| MW: | 186.2 D |
ab 40,00 €
Panobinostat
Artikelnummer: Cay13280-10
Panobinostat is a pan-inhibitor of histone deacetylases (HDACs, Kis = 0.6-31 nM for HDAC1-11). It inhibits growth in a panel of 37 human or mouse lung cancer cell lines, including small cell lung cancer (SCLC), non-small cell lung cancer (NSCLC), and mesothelioma cells (IC50s = 4-175, 5-310, and 5-470 nM,...
| Schlagworte: | LBH-589, (2E)-N-hydroxy-3-[4-[[[2-(2-methyl-1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2-propenamide |
| Anwendung: | HDAC inhibitor |
| CAS | 404950-80-7 |
| MW: | 349.4 D |
ab 39,00 €