NAG-thiazoline

NAG-thiazoline is an inhibitor of O-GlcNAcase (OGA, Ki = 180 nM). It is active against V. campbellii (MIC = 0.5 µM).Formal Name: (3aR,5R,6S,7R,7aR)-3a,6,7,7a-tetrahydro-5-(hydroxymethyl)-2-methyl-5H-pyrano[3,2-d]thiazole-6,7-diol. CAS Number: 179030-22-9. Synonyms: GlcNAc-thiazoline. Molecular Formula: C8H13NO4S. Formula Weight: 219.3. Purity: >98%. Formulation: (Request formulation change), A solution in ethanol. Solubility: DMF: 30 mg/ml, DMSO: 25 mg/ml, Ethanol: 30 mg/ml, PBS (pH 7.2): 5 mg/ml. SMILES: O[C@@H]1[C@]2([H])[C@](SC(C)=N2)([H])O[C@@H]([C@H]1O)CO. InChi Code: InChI=1S/C8H13NO4S/c1-3-9-5-7(12)6(11)4(2-10)13-8(5)14-3/h4-8,10-12H,2H2,1H3/t4-,5-,6-,7-,8-/m1/s1. InChi Key: DRHXTSWSUAJOJZ-FMDGEEDCSA-N.