ML-031

Sphingosine-1-phosphate (S1P) is a bioactive lipid that exhibits a broad spectrum of biological activities including cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis. It exerts its activity by binding to five distinct G protein-coupled receptors, S1P1/EDG-1, S1P2/EDG-5, S1P3/EDG-3, S1P4/EDG-6, and S1P5/EDG-8. ML-031 is one of the first indentified agonists of S1P2 demonstrating an EC50 value of 1 µM in a S1P reporter assay.Formal Name: 1-[2-[2,5-dimethyl-1-(phenylmethyl)-1H-pyrrol-3-yl]-2-oxoethyl]-2,5-pyrrolidinedione. CAS Number: 852230-33-2. Synonyms: CID-2113511. Molecular Formula: C19H20N2O3. Formula Weight: 324.4. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMSO: 5 mg/ml, Ethanol: 5 mg/ml. lambdamax: 251, 293 nm. SMILES: CC1=CC(C(CN2C(CCC2=O)=O)=O)=C(C)N1CC3=CC=CC=C3. InChi Code: InChI=1S/C19H20N2O3/c1-13-10-16(17(22)12-21-18(23)8-9-19(21)24)14(2)20(13)11-15-6-4-3-5-7-15/h3-7,10H,8-9,11-12H2,1-2H3. InChi Key: JRESCQKIRPOOEM-UHFFFAOYSA-N.