Zu "K04292" wurden 37 Artikel gefunden!
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CYM 5520
Artikelnummer: Cay17638-1
Sphingosine-1-phosphate (S1P, Cay-62570) is an extracellular lipid mediator whose major effects are mediated through five distinct G protein-coupled receptors, S1P1/EDG-1, S1P2/EDG-5, S1P3/EDG-3, S1P4/EDG-6, and S1P5/EDG-8. S1P2 has been implicated in multiple biological functions, including Rho activation,...
| Schlagworte: | 1-[2-[2,5-dimethyl-1-(phenylmethyl)-1H-pyrrol-3-yl]-2-oxoethyl]-1,6-dihydro-6-oxo-3-pyridinecarbonitrile |
| Anwendung: | Noncompetitive allosteric S1PR2 agonist |
| CAS | 1449747-00-5 |
| MW: | 345.4 D |
ab 49,00 €
Lipid-based Drug Delivery-Tools
Sphingosine-1-phosphate (d16:1)
Artikelnummer: Cay9002921-500
C16 Sphingosine-1-phosphate (C16 S1P) is a derivative of sphingosine-1-phosphate (S1P, Cay-62570) that binds to S1P1/EDG-1, S1P3/EDG-3, and S1P2/EDG-5 receptors with affinities of 115%, 83%, and 103%, respectively, relative to S1P in CHO cells. C16 S1P was increased in postmortem primary open angle glaucoma...
| Schlagworte: | C16 S1P, C16 Sphingosine-1-phosphate, S1P (d16:1), 2S-amino-1-(dihydrogen phosphate), 4E-hexadecene-1,3R-diol |
| Anwendung: | S1PR1/S1PR2/S1PR3 ligand |
| CAS | 709026-60-8 |
| MW: | 351.4 D |
ab 305,00 €
ML-031
Artikelnummer: Cay15171-1
Sphingosine-1-phosphate (S1P) is a bioactive lipid that exhibits a broad spectrum of biological activities including cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis. It exerts its activity by binding to five distinct G protein-coupled receptors, S1P1/EDG-1, S1P2/EDG-5,...
| Schlagworte: | CID-2113511, 1-[2-[2,5-dimethyl-1-(phenylmethyl)-1H-pyrrol-3-yl]-2-oxoethyl]-2,5-pyrrolidinedione |
| Anwendung: | S1P2 agonist |
| CAS | 852230-33-2 |
| MW: | 324.4 D |
ab 67,00 €
Human S1P2 / EDG5 ELISA Kit
Artikelnummer: G-HUFI00626.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
698,00 €
Mouse S1P2 / EDG5 ELISA Kit
Artikelnummer: G-MOFI00221.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
698,00 €
Anti-S1PR2
Artikelnummer: NSJ-R34953-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Sphingosine-1-phosphate receptor 2 Protein function: Receptor for the lysosphingolipid sphingosine 1- phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological...
| Schlagworte: | Anti-EDG5, Anti-S1P2, Anti-S1PR2, Anti-S1P receptor 2, Anti-S1P receptor Edg-5, Anti-Sphingosine 1-phosphate receptor 2,... |
| Anwendung: | WB, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human, mouse, rat |
836,00 €
Anti-S1PR2
Artikelnummer: NSJ-F46905-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. This gene encodes a member of the G protein-coupled receptors, as well as the EDG family of proteins. This protein participates in sphingosine 1-phosphate-induced cell proliferation, survival, and transcriptional activation Protein function: Receptor for the...
| Schlagworte: | Anti-EDG5, Anti-S1P2, Anti-S1PR2, Anti-S1P receptor 2, Anti-S1P receptor Edg-5, Anti-Sphingosine 1-phosphate receptor 2,... |
| Anwendung: | WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 361,00 €
CYM 5478
Artikelnummer: Cay29024-1
CYM 5478 is a sphingosine-1-phosphate receptor 2 (S1P2) agonist (EC50 = 0.78 µM in a reporter assay). It is selective for S1P2 over S1P1 and S1P3-5 in a TGFalpha-shedding assay (EC50s = 119, 1,690, 1,950, >10,000, and >10,000 nM, respectively). CYM 5478 (0.1-10 µM) reduces serum starvation-induced decreases in C6...
| Schlagworte: | 1-[2-[2,5-dimethyl-1-(phenylmethyl)-1H-pyrrol-3-yl]-2-oxoethyl]-5-(trifluoromethyl)-2(1H)-pyridinone |
| Anwendung: | Sphingosine-1-phosphate receptor 2 (S1P2) agonist |
| CAS | 870762-83-7 |
| MW: | 388.4 D |
ab 139,00 €
D-erythro/L-threo Lysosphingomyelin (d18:1)
Artikelnummer: Cay31557-50
Lysosphingomyelin is an endogenous bioactive sphingolipid and a constituent of lipoproteins. It is produced by the removal of the acyl group from sphingomyelin by a deacylase and acts as a precursor in the biosynthesis of sphingosine-1-phosphate (S1P, Cay-62570). D-erythro Lysosphingomyelin is an agonist of the S1P...
| Schlagworte: | D-erythro/L-threo Lyso SM(18:1), D-erythro/L-threo Sphingosine-1-Phosphocholine (d18:1),... |
| Anwendung: | Bioactive sphingolipid mixture |
| CAS | 82970-80-7 |
| MW: | 464.6 D |
ab 289,00 €
GLPG2938
Artikelnummer: Cay34318-1
GLPG2938 is sphingosine-1-phosphate receptor 2 (S1P2) antagonist. It inhibits S1P-induced calcium flux in CHO cells overexpressing human S1P2 (IC50 = 8.8 nM). GLPG2938 inhibits S1P-induced IL-8 release in HFL1 cells (IC50 = 0.6 nM) and S1P-induced contraction of human lung fibroblasts. In vivo, GLPG2938 (3, 10, and...
| Schlagworte: | N-[2-ethoxy-6-(trifluoromethyl)-4-pyridinyl]-N'-[[5-methyl-6-[1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]-3-pyridazinyl]... |
| Anwendung: | S1P2 antagonist |
| CAS | 2130996-00-6 |
| MW: | 503.4 D |
ab 93,00 €
Mouse S1PR2 (Sphingosine 1 Phosphate Receptor 2) ELISA Kit
Artikelnummer: ELK-ELK7434.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse S1PR2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse S1PR2. Next,...
| Schlagworte: | Edg5, S1P2, S1pr2, S1P receptor 2, S1P receptor Edg-5, Lysophospholipid receptor B2, Sphingosine 1-phosphate receptor 2,... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
ab 374,00 €
Sphingosine 1-phosphate receptor 2 (S1pr2), rat, recombinant
Artikelnummer: CSB-CF020651RA.100
Organism: Rattus norvegicus (Rat). Source: in vitro E.coli expression system. Expression Region: 1-352aa. Protein Length: Full Length. Tag Info: C-terminal 10xHis-tagged. Target Protein Sequence: MGGLYSEYLN PEKVQEHYNY TKETLDMQET PSRKVASAFI IILCCAIVVE NLLVLIAVAR NSKFHSAMYL FLGNLAASDL LAGVAFVANT LLSGPVTLSL TPLQWFAREG...
| Schlagworte: | S1P2, Edg5, AGR16, S1pr2, S1P receptor 2, S1P receptor Edg-5, G-protein coupled receptor H218, Sphingosine 1-phosphate... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli in vitro |
| Ursprungsart: | rat |
| MW: | 41.6 kD |
ab 943,00 €