CID-797718

CID-797718 is a protein kinase D1 (PKD1) inhibitor (IC50 = 7 µM). It also inhibits CDK activating kinase (CAK) and polo-like kinase 1 (PLK1) but has no activity at AKT (IC50s = 8.4, 21.9, and >50 µM, respectively). CID-797718 inhibits PKD1 activity in LNCaP cells with an IC50 value of 0.21 µM. CID7-97718 is a byproduct in the synthesis of CID-755673 (Cay-15924).Formal Name: 1,2,3,4-tetrahydro-9-hydroxy-5H-[1]benzopyrano[3,4-b]pyridin-5-one. CAS Number: 370586-05-3. Molecular Formula: C12H11NO3. Formula Weight: 217.2. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 20 mg/ml, Ethanol: 1 mg/ml. lambdamax: 215, 250, 347 nm. SMILES: OC1=CC=C2C(C(CCCN3)=C3C(O2)=O)=C1. InChi Code: InChI=1S/C12H11NO3/c14-7-3-4-10-9(6-7)8-2-1-5-13-11(8)12(15)16-10/h3-4,6,13-14H,1-2,5H2. InChi Key: VDZXTSOINJESSP-UHFFFAOYSA-N.