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Zu "K06070" wurden 109 Artikel gefunden!
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Artikelnummer: ELK-ES6785.100
PRKD1 is a serine/threonine kinase that regulates a variety of cellular functions, including membrane receptor signaling, transport at the Golgi, protection from oxidative stress at the mitochondria, gene transcription, and regulation of cell shape, motility, and adhesion (summary by Eiseler et al., 2009 [PubMed...
Schlagworte: | Anti-phospho-PKD, Anti-phospho-PRKD1, Anti-phospho-nPKC-mu, Anti-phospho-nPKC-D1, EC=2.7.11.13, Anti-phospho-Protein... |
Anwendung: | WB, IHC, IF, ELISA |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
169,00 €
ab 152,10 €
-10 %
Artikelnummer: AG-CR1-3550-M001
CRT0066101 is an inhibitor of all three PKD isoforms (IC50s = 1, 2.5, and 2 nM for PKD1, PKD2 and PKD3, respectively). It exhibits selectivity for PKD against a panel of >90 protein kinases, including PKCalpha, PKBalpha, MEK, ERK, c-Raf, c-Src and c-Abl. PKD family members play an important role in regulating...
Schlagworte: | 2-[4-[[(2R)-2-Aminobutyl]amino]-2-pyrimidinyl]-4-(1-methyl-1H-pyrazol-4-yl)-phenol . hydrochloride |
Anwendung: | Protein kinase D (PKD1 / PKD2 / PKD3) inhibitor |
CAS | 1781742-22-0 |
MW: | 447.8 D |
50,00 €
45,00 €
Artikelnummer: A300-073A
Protein function: Serine/threonine-protein kinase that converts transient diacylglycerol (DAG) signals into prolonged physiological effects downstream of PKC, and is involved in the regulation of cell proliferation via MAPK1/3 (ERK1/2) signaling, oxidative stress- induced NF-kappa-B activation, inhibition of HDAC7...
Schlagworte: | Anti-PKD2, Anti-PRKD2, Anti-HSPC187, Anti-nPKC-D2, EC=2.7.11.13, Anti-Serine/threonine-protein kinase D2 |
Anwendung: | WB, IP |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 164,00 €
Artikelnummer: A300-074A
Protein function: Serine/threonine-protein kinase that converts transient diacylglycerol (DAG) signals into prolonged physiological effects downstream of PKC, and is involved in the regulation of cell proliferation via MAPK1/3 (ERK1/2) signaling, oxidative stress- induced NF-kappa-B activation, inhibition of HDAC7...
Schlagworte: | Anti-PKD2, Anti-PRKD2, Anti-HSPC187, Anti-nPKC-D2, EC=2.7.11.13, Anti-Serine/threonine-protein kinase D2 |
Anwendung: | WB, IP, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 164,00 €
Artikelnummer: Cay15337-1
Protein kinase D (PKD) is a serine/threonine protein kinase that is activated by diacylglycerol, commonly downstream of PKC signaling. The three human PKD isoforms target a variety of proteins to alter cell proliferation, survival, invasion, and protein transport. CRT0066101 is an inhibitor of all three PKD isoforms...
Schlagworte: | 2-[4-[[(2R)-2-aminobutyl]amino]-2-pyrimidinyl]-4-(1-methyl-1H-pyrazol-4-yl)-phenol, trihydrochloride |
Anwendung: | PKD inhibitor |
CAS | 1781742-22-0 |
MW: | 447.8 D |
ab 46,00 €
Artikelnummer: Cay18002-5
kb NB 142-70 is a selective inhibitor of protein kinase D (PKD) with IC50 values of 28.3, 58.7, and 53.2 nM for PKD1, 2, and 3, respectively. It has been shown to inhibit prostate cancer cell migration and invasion, as well as reduce wound healing in vitro.Formal Name:...
Schlagworte: | 3,4-dihydro-9-hydroxy-[1]benzothieno[2,3-f]-1,4-thiazepin-5(2H)-one |
Anwendung: | Protein kinase D inhibitor |
CAS | 1233533-04-4 |
MW: | 251.3 D |
ab 127,00 €
Artikelnummer: Cay18532-5
Protein kinase D (PKD) is a serine/threonine protein kinase that is activated by diacylglycerol, commonly downstream of PKC signaling. The three human PKD isoforms target a variety of proteins to alter cell proliferation, survival, invasion, and protein transport. CRT5 is a pyrazine benzamide that prevents...
Schlagworte: | CRT0066051, 3-[6-amino-5-(6-ethoxy-2-naphthalenyl)-3-pyridinyl]-N-[2-(dimethylamino)ethyl]-benzamide |
Anwendung: | PKD activation inhibitor |
CAS | 1034297-58-9 |
MW: | 454.6 D |
ab 43,00 €
Artikelnummer: Cay15924-1
Protein kinase D (PKD) is a serine/threonine protein kinase that is activated by diacylglycerol, commonly downstream of PKC signaling. The three human PKD isoforms target a variety of proteins to alter cell proliferation, survival, invasion, and protein transport. CID-755673 is a small molecule inhibitor of PKD...
Schlagworte: | 2,3,4,5-tetrahydro-7-hydroxy-1H-benzofuro[2,3-c]azepin-1-one |
Anwendung: | PKD inhibitor |
CAS | 521937-07-5 |
MW: | 217.2 D |
ab 66,00 €
Artikelnummer: Cay33707-1
BPKDi is an inhibitor of protein kinase D (PKD, IC50s = 1, 9, and 1 nM for PKD1, PKD2, and PKD3, respectively). It is selective for PKD over PKCdelta and PKCepsilon, as well as over a panel of additional calcium/calmodulin-dependent protein kinase (CaMK) superfamily members, at 1 µM. It inhibits...
Schlagworte: | 2'-(cyclohexylamino)-6-(1-piperazinyl)-[2,4'-bipyridine]-4-carboxamide |
Anwendung: | PKD inhibitor |
CAS | 1201673-28-0 |
MW: | 380.5 D |
ab 163,00 €
Artikelnummer: Cay23428-5
CID-797718 is a protein kinase D1 (PKD1) inhibitor (IC50 = 7 µM). It also inhibits CDK activating kinase (CAK) and polo-like kinase 1 (PLK1) but has no activity at AKT (IC50s = 8.4, 21.9, and >50 µM, respectively). CID-797718 inhibits PKD1 activity in LNCaP cells with an IC50 value of 0.21 µM. CID7-97718 is a...
Schlagworte: | 1,2,3,4-tetrahydro-9-hydroxy-5H-[1]benzopyrano[3,4-b]pyridin-5-one |
Anwendung: | Serine/threonine-protein kinase D1 inhibitor |
CAS | 370586-05-3 |
MW: | 217.2 D |
ab 43,00 €
Artikelnummer: ARG51581.100
Protein function: Serine/threonine-protein kinase that converts transient diacylglycerol (DAG) signals into prolonged physiological effects downstream of PKC, and is involved in the regulation of MAPK8/JNK1 and Ras signaling, Golgi membrane integrity and trafficking, cell survival through NF-kappa-B activation, cell...
Schlagworte: | Anti-phospho-PKD, Anti-phospho-PRKD1, Anti-phospho-nPKC-mu, Anti-phospho-nPKC-D1, EC=2.7.11.13, Anti-phospho-Protein... |
Anwendung: | ICC, IF, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
ab 436,00 €
Artikelnummer: ARG51598.100
Protein function: Serine/threonine-protein kinase that converts transient diacylglycerol (DAG) signals into prolonged physiological effects downstream of PKC, and is involved in the regulation of MAPK8/JNK1 and Ras signaling, Golgi membrane integrity and trafficking, cell survival through NF-kappa-B activation, cell...
Schlagworte: | Anti-phospho-PKD, Anti-phospho-PRKD1, Anti-phospho-nPKC-mu, Anti-phospho-nPKC-D1, EC=2.7.11.13, Anti-phospho-Protein... |
Anwendung: | ICC, IF, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
ab 436,00 €