CAY10685

CAY10685 is a cell-active analog of the lysine acetyltransferase inhibitor CPTH2 (Cay-12086) that contains an alkyne moiety for use in click chemistry reactions. Its ability to inhibit N-acetyltransferase 10 activity has been used to modulate chromatin organization in order to study changes in nuclear architecture associated with cancer and certain laminopathies.Formal Name: cyclopentanone, 2-[4-(4-chlorophenyl)-2-thiazolyl]-2-(2-propyn-1-yl)hydrazone. CAS Number: 1613116-16-7. Synonyms: Click TagTM CAY10685. Molecular Formula: C17H16ClN3S. Formula Weight: 329.8. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 10 mg/ml, DMF:PBS(pH7.2) (1:2): 0.3 mg/ml, DMSO: 5 mg/ml, Ethanol: 3 mg/ml. lambdamax: 249 nm. SMILES: ClC1=CC=C(C2=CSC(N(CC#C)/N=C3CCCC\3)=N2)C=C1. InChi Code: InChI=1S/C17H16ClN3S/c1-2-11-21(20-15-5-3-4-6-15)17-19-16(12-22-17)13-7-9-14(18)10-8-13/h1,7-10,12H,3-6,11H2. InChi Key: JDLMHEOHMFFSDW-UHFFFAOYSA-N.