2-furoyl-LIGRLO amide (trifluoroacetate salt)

2-furoyl-LIGRLO amide is a potent and selective agonist of the proteinase-activated receptor, PAR2 (pD2 = 7.0). It does not activate PAR1 or PAR4. Through its effects on PAR2, 2-furoyl-LIGRLO amide produces a concentration-dependent relaxation of arteries previously contracted with alpha1 adrenergic receptor agonists.Formal Name: N-(2-furanylcarbonyl)-L-leucyl-L-isoleucylglycyl-L-arginyl-L-leucyl-L-ornithinamide, trifluoroacetate. Molecular Formula: C36H63N11O8 . XCF3COOH. Formula Weight: 778.0. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: Water: 1 mg/ml. SMILES: O=C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(C)C)C(N[C@@H](CCCN)C(N)=O)=O)=O)CNC([C@@H](NC([C@@H](NC(C1=CC=CO1)=O)CC(C)C)=O)[C@@H](C)CC)=O.FC(F)(C(O)=O)F. InChi Code: InChI=1S/C36H63N11O8.C2HF3O2/c1-7-22(6)29(47-33(52)26(18-21(4)5)46-34(53)27-13-10-16-55-27)35(54)42-19-28(48)43-24(12-9-15-41-36(39)40)31(50)45-25(17-20(2)3)32(51)44-23(30(38)49)11-8-14-37,3-2(4,5)1(6)7/h10,13,16,20-26,29H,7-9,11-12,14-15,17-19,37H2,1-6H3,(H2,38,49)(H,42,54)(H,43,48)(H,44,51)(H,45,50)(H,46,53)(H,47,52)(H4,39,40,41),(H,6,7)/t22-,23-,24-,25-,26-,29-,/m0./s1. InChi Key: GGAPZASUUCRPNF-OIQQVIETSA-N.