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Zu "K04234" wurden 30 Artikel gefunden!
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Artikelnummer: DIM-PME101118.10
Recombinant human F2RL1 protein with C-terminal human Fc tag. F2RL1(Ser37-Gly71) hFc(Glu99-Ala330), Protein function: Receptor for trypsin and trypsin-like enzymes coupled to G proteins (PubMed:28445455). Its function is mediated through the activation of several signaling pathways including phospholipase C (PLC),...
Schlagworte: | GPR11, PAR2 |
Exprimiert in: | Human cells |
Ursprungsart: | human |
CAS | 12 |
MW: | 29.7 kD |
ab 144,00 €
Artikelnummer: DIM-FLP100036.10
Discover a breakthrough in membrane protein research and drug development with DIMA Biotech's Synthetic Nanodiscs. Traditional methods struggle with challenges in obtaining water-soluble and bioactive forms of multi-transmembrane proteins. Our innovative polymer-based Nanodisc platform offers a game-changing...
Schlagworte: | GPR11, F2RL1, GPR11, PAR2, Human F2RL1 full length protein-synthetic nanodisc |
Anwendung: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
Exprimiert in: | Human cells |
Ursprungsart: | human |
MW: | 44.1 kD |
ab 1.260,00 €
Artikelnummer: Cay37553-100
I-191 is an antagonist of proteinase-activated receptor 2 (PAR2, IC50 = 72.4 nM in HT-29 cells expressing the human receptor). It inhibits trypsin-induced calcium release in HT-29 cells (IC50 = 200 nM for the human receptor). I-191 (0.1, 1, and 10 µM) reduces the migration of HT-29 cells in a scratch assay. It...
Schlagworte: | 4-[[8-(1,1-dimethylethyl)-6-(4-fluorophenyl)imidazo[1,2-b]pyridazin-2-yl]carbonyl]-3,3-dimethyl-2-piperazinone |
Anwendung: | PAR2 antagonist |
CAS | 1690172-25-8 |
MW: | 423.5 D |
ab 204,00 €
Artikelnummer: ELK-ELK1638.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat PAR2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat PAR2. Next,...
Schlagworte: | Par2, PAR-2, F2rl1, Thrombin receptor-like 1, Proteinase-activated receptor 2, Coagulation factor II receptor-like 1 |
Anwendung: | ELISA |
Spezies-Reaktivität: | rat |
ab 365,00 €
Artikelnummer: ELK-ELK1639.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse PAR2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse PAR2. Next,...
Schlagworte: | PAR-2, F2rl1, Gpcr11, Thrombin receptor-like 1, G-protein coupled receptor 11, Proteinase-activated receptor 2,... |
Anwendung: | ELISA |
Spezies-Reaktivität: | mouse |
ab 365,00 €
Artikelnummer: ELK-ELK2416.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human PAR2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human PAR2. Next,...
Schlagworte: | GPR11, F2RL1 |
Anwendung: | ELISA |
Spezies-Reaktivität: | human |
ab 365,00 €
Artikelnummer: Cay16723-1
Proteinase-activated receptor 2 (PAR2) is a G protein-coupled receptor that is cleaved by serine proteases, resulting in self-activation of the receptor by a tethered ligand. The ligand corresponds to residues 39-44 (SLIGRL in mouse PAR-2). SLIGRL-NH2 is a recombinant peptide that activates PAR2 (EC50 = ~5 µM),...
Schlagworte: | L-seryl-L-leucyl-L-isoleucylglycyl-L-arginyl-L-Leucinamide, trifluoroacetate salt |
Anwendung: | PAR-2 activator |
MW: | 656.8 D |
ab 50,00 €
Artikelnummer: Cay14709-5
FSLLRY-amide is a peptide antagonist of protease-activated receptor (PAR) 2 which blocks activation by trypsin (IC50 = ~50 µM) but not by the synthetic agonist SLIGRL-NH2 (Cay-16723). It does not affect thrombin-induced activation of PAR1 or trypsin-mediated proteolysis of casein. It can be used to study PAR2 action...
Schlagworte: | L-phenylalanyl-L-seryl-L-leucyl-L-leucyl-L-arginyl-L-tyrosinamide |
Anwendung: | PAR2 antagonist |
CAS | 245329-02-6 |
MW: | 797 D |
ab 119,00 €
Artikelnummer: Cay17736-5
AC-55541 is a proteinase-activated receptor 2 (PAR2) agonist that displays no activity at other PAR subtypes or at over 30 other receptors involved in nociception and inflammation. It stimulates cell proliferation, phosphatidylinositol hydrolysis, and calcium mobilization in in vitro functional assays (pEC50s = 6.7,...
Schlagworte: | alpha-(benzoylamino)-3,4-dihydro-4-oxo-1-phthalazineacetic acid 2E-[1-(3-bromophenyl)ethylidene]hydrazide |
Anwendung: | PAR2 agonist |
CAS | 916170-19-9 |
MW: | 518.4 D |
ab 60,00 €
Artikelnummer: Cay14594-1
2-furoyl-LIGRLO amide is a potent and selective agonist of the proteinase-activated receptor, PAR2 (pD2 = 7.0). It does not activate PAR1 or PAR4. Through its effects on PAR2, 2-furoyl-LIGRLO amide produces a concentration-dependent relaxation of arteries previously contracted with alpha1 adrenergic receptor...
Schlagworte: | N-(2-furanylcarbonyl)-L-leucyl-L-isoleucylglycyl-L-arginyl-L-leucyl-L-ornithinamide, trifluoroacetate |
Anwendung: | PAR2 agonist |
MW: | 778 D |
156,00 €
Artikelnummer: G-MOFI01027.96
Anwendung: | ELISA |
Spezies-Reaktivität: | mouse |
694,00 €
Artikelnummer: NSJ-R32144
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Protease activated receptor 2 (PAR2), also known ascoagulation factor II (thrombin) receptor-like 1 (F2RL1) or G-protein coupled receptor 11 (GPR11), is a protein that in humans is encoded by the F2RL1 gene. F2RL1 is a member of the large family of...
Schlagworte: | Anti-F2RL1, Anti-GPR11, PAR2 Antibody / F2RL1 / Thrombin Receptor-like 1 |
Anwendung: | WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
755,00 €