Perforin (human) ELISA Kit

Diaclone ELISA Kits include pre-coated strip plates, biotinylated secondary antibody, standards, controls (where applicable), buffers, streptavidin-HRP, TMB, stop reagents, and a detailed procedure., Assay Range: 62.5-2000 pg/ml, Sensitivity: 40 pg/ml, Cross reaction: No cross reactivity with Trail, TRAIL R3, TRAIL R4, Granzyme B, TNFalpha, IFNgamma, Fas, Fas L, IL-1b, IL-2, Incubation time: 2h45, Sample Types: Supernatant, Buffered Solutions, Not suitable for use with serum and plasma., Sample Size: 100 µl Protein function: Plays a key role in secretory granule-dependent cell death, and in defense against virus-infected or neoplastic cells. Plays an important role in killing other cells that are recognized as non-self by the immune system, e.g. in transplant rejection or some forms of autoimmune disease. Can insert into the membrane of target cells in its calcium-bound form, oligomerize and form large pores. Promotes cytolysis and apoptosis of target cells by facilitating the uptake of cytotoxic granzymes. [The UniProt Consortium]