Perforin (human) ELISpot Set

Diaclone ELISpot Sets include capture and detection antibodies, Streptavidin - Alkaline Phosphatase conjugated, BSA, BCIP/NTB, blocking reagent, and no, 1, 5, 10, 15, or 20 sterile or non-sterile plates, , Incubation time: 3h after cell stimulation, , Additional info: To receive kit plus non-sterile plates (MSIPN), please add 'P' at the end of the Cat N°. To receive kit plus sterile plates (MSIPS), please add 'S' at the end of the Cat N°. Spots read visually or with reader Protein function: Plays a key role in secretory granule-dependent cell death, and in defense against virus-infected or neoplastic cells. Plays an important role in killing other cells that are recognized as non-self by the immune system, e.g. in transplant rejection or some forms of autoimmune disease. Can insert into the membrane of target cells in its calcium-bound form, oligomerize and form large pores. Promotes cytolysis and apoptosis of target cells by facilitating the uptake of cytotoxic granzymes. [The UniProt Consortium]