Mouse BMP-2 ELISA Kit

Natural and recombinant mouse BMP-2. There is no detectable cross-reactivity with other relevant proteins. Protein function: Induces cartilage and bone formation. Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3- EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4. [The UniProt Consortium]