Anti-NMDA NR2B Subunit

Anti-NMDA NR2B Subunit
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
600-401-C87 10 µg - -

6 - 10 Werktage*

684,00 €
 
Anti-NMDA 2B antibody is directed against NMDA receptor protein. The antibody was affinity... mehr
Produktinformationen "Anti-NMDA NR2B Subunit"
Anti-NMDA 2B antibody is directed against NMDA receptor protein. The antibody was affinity purified from monospecific antiserum by immunoaffinity purification. The antibody Recognizes human, mouse and rat forms of the NR2B subunits of NMDAR. Immunolabeling is blocked by pre-adsorption of antibody with the fusion protein used to generate the antibody. No reactivity towards the NR2A and NR2C subunits was seen. Protein function: NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. In concert with DAPK1 at extrasynaptic sites, acts as a central mediator for stroke damage. Its phosphorylation at Ser-1303 by DAPK1 enhances synaptic NMDA receptor channel activity inducing injurious Ca2 influx through them, resulting in an irreversible neuronal death. [The UniProt Consortium]
Schlagworte: Anti-NR2B, Anti-GluN2B, Anti-Grin2b, Anti-NMDAR2B, Anti-Glutamate receptor ionotropic, NMDA 2B, Anti-N-methyl D-aspartate receptor subtype 2B, Anti-Glutamate [NMDA] receptor subunit epsilon-2
Hersteller: Rockland Immunochemicals
Hersteller-Nr: 600-401-C87

Eigenschaften

Anwendung: IHC, IP, WB
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: rat, mouse, human
Immunogen: fusion protein from the C-terminal region NR2B subunit.
Format: Purified

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +20°C (International: +20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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