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Zu "K05210" wurden 101 Artikel gefunden!
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Artikelnummer: Cay38788-1
BZAD-01 is an antagonist of NR2B subunit-containing NMDA receptors (Ki = 72 nM). It is selective for NR2B subunit-containing NMDA receptors over those containing NR2A subunits in a calcium mobilization assay (IC50s = 47 and >10,000 nM, respectively). Oral administration of BZAD-01 reduces hyperalgesia induced by...
Schlagworte: | 4-(trifluoromethoxy)-N-[[2-(trifluoromethyl)phenyl]methyl]-benzenecarboximidamide |
Anwendung: | NR2B subunit-containing NMDA receptor antagonist |
CAS | 305339-41-7 |
MW: | 362.3 D |
ab 39,00 €
Artikelnummer: ELK-ELK8400.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse GRIN2B. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse GRIN2B....
Schlagworte: | NR2B, Grin2b, GluN2B, NMDAR2B, Glutamate receptor ionotropic, NMDA 2B, N-methyl D-aspartate receptor subtype 2B, Glutamate... |
Anwendung: | ELISA |
Spezies-Reaktivität: | mouse |
ab 365,00 €
Artikelnummer: ELK-ELK4421.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human GRIN2B. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human GRIN2B....
Schlagworte: | NR3, hNR3, NR2B, GRIN2B, GluN2B, NMDAR2B, Glutamate receptor ionotropic, NMDA 2B, N-methyl-D-aspartate receptor subunit 3,... |
Anwendung: | ELISA |
Spezies-Reaktivität: | human |
ab 365,00 €
Artikelnummer: Cay14539-50
D-AP5 is a selective N-methyl-D-aspartate (NMDA) receptor antagonist (Kd = 1.4 µM) that competitively inhibits the glutamate binding site of NMDA receptors. Whereas D-AP5 is the active (-)-stereoisomer, its (+)-isomer (L-AP5) demonstrates considerably less potent NMDA receptor antagonist activity. AP5 has been...
Schlagworte: | D-2-Amino-5-Phosphonovaleric Acid, D-APV, 5-phosphono-D-norvaline |
Anwendung: | NMDA receptor antagonist |
CAS | 79055-68-8 |
MW: | 197.1 D |
ab 77,00 €
Artikelnummer: Cay14540-50
DL-AP5 is the racemic version of the selective N-methyl-D-aspartate (NMDA) receptor antagonist, D-AP5 (Cay-14539). Whereas D-AP5 is the active (-)-stereoisomer that competitively inhibits the glutamate binding site of NMDA receptors (Kd = 1.4 µM), the (+)-isomer (L-AP5) demonstrates considerably less potent NMDA...
Schlagworte: | 2-APV, DL-2-Amino-5-Phosphonovaleric acid, 5-phosphono-norvaline |
Anwendung: | NMDA receptor antagonist |
CAS | 76326-31-3 |
MW: | 197.1 D |
ab 64,00 €
Artikelnummer: Cay14581-100
NMDA is a synthetic amino acid derivative that acts as a specific agonist at the NMDA receptor, mimicking the excitatory action of the endogenous ligand glutamate. Signaling through the NMDA receptor influences both neuronal plasticity and neurotoxicity. Repetitive activation of NMDA synapses leads to long-term...
Schlagworte: | N-Methyl-D-Aspartic Acid, N-methyl-D-aspartic acid |
Anwendung: | NMDA receptor agonist |
CAS | 6384-92-5 |
MW: | 147.1 D |
ab 82,00 €
Artikelnummer: 612-401-C88
Anti-NMDA NR2B Subunit pY1336 antibody is directed against NMDA 2B receptor protein. The antibody was affinity purified from monospecific antiserum by immunoaffinity purification. Anti-NMDA NR2B Subunit pY1336 antibody is specific for the phophorylated protein. Immunolabeling of the NMDAR NR2B subunit band is...
Schlagworte: | Anti-phospho-NR2B, Anti-phospho-GluN2B, Anti-phospho-Grin2b, Anti-phospho-NMDAR2B, Anti-phospho-Glutamate receptor... |
Anwendung: | IHC, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | rat |
684,00 €
Artikelnummer: 612-401-D92
Anti-NMDA R2B pT1252 antibody is directed against NMDA R2B protein. NMDA R2B pT1252 antibody was affinity purified from monospecific antiserum by immunoaffinity purification. The antibody is specific for the phophorylated NMDA R2B protein. Immunolabeling of the NMDA NR2B subunit band is blocked by the phosphopeptide...
Schlagworte: | Anti-phospho-NR2B, Anti-phospho-GluN2B, Anti-phospho-Grin2b, Anti-phospho-NMDAR2B, Anti-phospho-Glutamate receptor... |
Anwendung: | IHC, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | rat |
684,00 €
Artikelnummer: LKT-G1855.25
Gentiopicroside is one of the secoiridoid compound isolated from Gentiana lutea. It inhibits morphine dependence through downregulation of GluN2B-containing NMDA receptors in the NAc.
Schlagworte: | 4-[(3R)-3,4-Dihydro-8,8-dimethyl-2H,8H-benzo[1,2-b:3,4-b?]dipyran-3-yl]-1,3-benzenediol,... |
Anwendung: | GRIN2B NMDAR downregulation |
CAS | 20831-76-9 |
MW: | 356,32 D |
ab 175,00 €
Artikelnummer: Cay14184-25
Memantine is an NMDA receptor antagonist that blocks NMDA-induced currents in rat retinal ganglion cells by 90% when used at a concentration of 12 µM. It reverses inhibition of dephosphorylation of the synthetic tau phosphopeptide p17 (tau194-207) induced by the endogenous inhibitor of protein phosphatase 2A (PP2A)...
Schlagworte: | Akatinol, Axura, Ebix, Namenda, NSC 102290, SUN Y7017, 3,5-dimethyl-tricyclo[3.3.1.13,7]decan-1-amine, monohydrochloride |
Anwendung: | NMDA open-channel blocker |
CAS | 41100-52-1 |
MW: | 215.8 D |
ab 35,00 €
Artikelnummer: Cay18398-5
N-Methyl-D-aspartate (NMDA) receptors are calcium permeable ligand-gated channels of the central nervous system that are activated after binding of the co-agonists glutamate and glycine. Eliprodil is a non-competitive NMDA receptor antagonist that inhibits neuronal calcium channel currents. It is selective for NR2B...
Schlagworte: | SL 820715, alpha-(4-chlorophenyl)-4-[(4-fluorophenyl)methyl]-1-piperidineethanol |
Anwendung: | Selective NMDA glutamate receptor NR2B antagonist |
CAS | 119431-25-3 |
MW: | 347.9 D |
ab 82,00 €
Artikelnummer: Cay21364-25
Amantadine is an NMDA receptor antagonist with IC50 values of 0.93, 0.82, and 0.47 µM at -70 mV for NR1-1a/NR2A, NR1-1a/NR2B, and NR1-1a/NR2D subunit-containing recombinant receptors, respectively, expressed in HEK293 cells. It blocks the influenza A M2 proton channel (IC50 = 16 µM for the recombinant channel...
Schlagworte: | Adamantylamine, Aminoadamantane, NSC 83653, tricyclo[3.3.1.13,7]decan-1-amine, monohydrochloride |
Anwendung: | NMDA receptor antagonist, antiviral, M2 protein inhibitor |
CAS | 665-66-7 |
MW: | 187.7 D |
ab 43,00 €