Anti-EIF4E

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
E-AB-60650.60 60 µl -

7 - 16 Werktage*

218,00 €
E-AB-60650.120 120 µl -

7 - 16 Werktage*

356,00 €
E-AB-60650.200 200 µl -

7 - 16 Werktage*

574,00 €
 
The protein encoded by this gene is a component of the eukaryotic translation initiation factor... mehr
Produktinformationen "Anti-EIF4E"
The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants. Protein function: Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap. [The UniProt Consortium]
Schlagworte: Anti-eIF4E, Anti-EIF4E, Anti-eIF-4E, Anti-EIF4EL1, Anti-eIF-4F 25 kDa subunit, Anti-mRNA cap-binding protein, Anti-Eukaryotic translation initiation factor 4E, EIF4E Polyclonal Antibody
Hersteller: Elabscience
Hersteller-Nr: E-AB-60650

Eigenschaften

Anwendung: WB, IHC
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
Immunogen: A synthetic peptide of human EIF4E

Handhabung & Sicherheit

Lagerung: -20°C
Versand: 4°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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