Produkte von Indigo Biosciences

Indigo

Indigo Biosciences, Inc. wurde im Jahr 2005 in State College, PA von Dr. Jack Vanden Heuvel und Dr. Blake Peterson gegründet. Das biowissenschaftliche Unternehmen konzentriert sich auf Produkte und Dienstleistungen im Bereich Kernrezeptoren, die eine wichtige Klasse von therapeutischen Wirkstoffzielen darstellen. Hierbei stellen quantitative Aktivitäts-Assays noch immer eine besondere Herausforderung für die Biotechnologie dar. Die beiden Gründer des Unternehmens sind international anerkannte Spezialisten auf diesem Gebiet und nutzten ihre gesammelte Expertise in der Kernrezeptorbiologie, Toxikologie, medizinischer Chemie und Molekularbiologie, um die Technologie-Plattform für diese Produkte zu entwickeln.

Mehr unter: indigobiosciences.com

8 von 7 Seiten
Für die Filterung wurden keine Ergebnisse gefunden!
PPARalpha (mouse) Reporter Assay Kit
PPARalpha (mouse) Reporter Assay Kit

Artikelnummer: IB-M00111

This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the mouse peroxisome proliferator-activated receptor alpha (NR1C1), a ligand-dependent transcription factor commonly referred to as PPARA or mPPARalpha. INDIGO's reporter cells include...
Schlagworte: Ppara, Nr1c1, PPAR-alpha, Nuclear receptor subfamily 1 group C member 1, Peroxisome proliferator-activated receptor alpha
Anwendung: Functional activity screening
Reaktivität: Mouse
ab 1.121,00 €
Bewerten
PPARdelta (rat) Reporter Assay Kit
PPARdelta (rat) Reporter Assay Kit

Artikelnummer: IB-R00121

This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the rat peroxisome proliferator-activated receptor delta (NR1C2), a ligand-dependent transcription factor commonly referred to as PPARD or rPPARdelta. INDIGO's reporter cells include...
Schlagworte: Ppard, PPARb, Protein Ppard, Peroxisome proliferator-activated receptor beta, Peroxisome proliferator activated receptor...
Anwendung: Functional activity screening
Reaktivität: Rat
ab 1.121,00 €
Bewerten
RXRgamma (human) Reporter Assay Kit
RXRgamma (human) Reporter Assay Kit

Artikelnummer: IB-IB00821

This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the human retinoid X receptor gamma (NR2B3), a ligand-dependent transcription factor commonly referred to as RXRG or RXRgamma. INDIGO's reporter cells include the luciferase reporter...
Schlagworte: RXRG, NR2B3, Retinoid X receptor gamma, Retinoic acid receptor RXR-gamma, Nuclear receptor subfamily 2 group B member 3
Anwendung: Functional activity screening
Reaktivität: Human
ab 1.121,00 €
Bewerten
TRbeta (human) Reporter Assay Kit
TRbeta (human) Reporter Assay Kit

Artikelnummer: IB-IB01101

This nuclear receptor assay system utilizes proprietary human cells engineered to provide constitutive, high-level expression of the human thyroid hormone receptor beta (NR1A2), a ligand-dependent transcription factor commonly referred to as TRbeta. INDIGO's reporter cells include the luciferase reporter gene...
Schlagworte: THRB, ERBA2, c-erbA-2, c-erbA-beta, Thyroid hormone receptor beta, Nuclear receptor subfamily 1 group A member 2
Anwendung: Functional activity screening
Reaktivität: Human
ab 1.121,00 €
Bewerten
PXR (Rat) Reporter Assay System
PXR (Rat) Reporter Assay System

Artikelnummer: IB-R07001

Protein function: Nuclear receptor that binds and is activated by a variety of endogenous and xenobiotic compounds. Transcription factor that activates the transcription of multiple genes involved in the metabolism and secretion of potentially harmful xenobiotics, endogenous compounds and drugs. Response to specific...
Schlagworte: Pxr, Nr1i2, Pregnane X receptor, Orphan nuclear receptor PXR, Nuclear receptor subfamily 1 group I member 2
Anwendung: Functional activity screening
Reaktivität: Rat
ab 1.121,00 €
Bewerten
Live Cell Multiplex Assay Kit
Live Cell Multiplex Assay Kit

Artikelnummer: IB-LCM-01

The live cell multiplex (LCM) assay provides an efficient fluorescence-based method of quantifying the relative number of live cells resident in treated wells of an assay plate. While the LCM assay may be performed as a stand-alone assay, it is has been specifically optimized to be run in multiplex with any of...
Anwendung: LCM assay, Quantification of relative number of live cells
ab 203,00 €
Bewerten
LRH-1 (Human) Reporter Assay System
LRH-1 (Human) Reporter Assay System

Artikelnummer: IB-IB11001

Protein function: Binds to the sequence element 5'-AACGACCGACCTTGAG-3' of the enhancer II of hepatitis B virus genes, a critical cis-element of their expression and regulation. May be responsible for the liver-specific activity of enhancer II, probably in combination with other hepatocyte transcription factors. Key...
Schlagworte: B1F, hB1F, NR5A2, LRH-1, B1-binding factor, Liver receptor homolog 1, CYP7A promoter-binding factor, Hepatocytic...
Anwendung: Functional activity screening
Reaktivität: Human
ab 1.121,00 €
Bewerten
RXRalpha (human) Reporter Assay Kit
RXRalpha (human) Reporter Assay Kit

Artikelnummer: IB-IB00801

This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the human retinoid X receptor alpha (NR2B1), a ligand-dependent transcription factor commonly referred to as RXRA or RXRalpha. INDIGO's reporter cells include the luciferase reporter...
Schlagworte: RXRA, NR2B1, Retinoid X receptor alpha, Retinoic acid receptor RXR-alpha, Nuclear receptor subfamily 2 group B member 1
Anwendung: Functional activity screening
Reaktivität: Human
ab 1.121,00 €
Bewerten
NF-kappaB (Human) Reporter Assay System
NF-kappaB (Human) Reporter Assay System

Artikelnummer: IB-IB09001

Anwendung: Functional activity screening
Reaktivität: Human
ab 1.121,00 €
Bewerten
8 von 7 Seiten
Zuletzt angesehen