Produkte von Indigo Biosciences
Indigo Biosciences, Inc. wurde im Jahr 2005 in State College, Pennsylvania von Dr. Jack Vanden Heuvel und Dr. Blake Peterson gegründet. Das biowissenschaftliche Unternehmen konzentriert sich auf Produkte und Dienstleistungen im Bereich in vitro-Toxikologie und Kernrezeptoren. Diese Rezeptoren stellen eine wichtige Klasse von therapeutischen Wirkstoffzielen dar. Hierbei sind quantitative Aktivitätsassays noch immer eine besondere Herausforderung für die Biotechnologie. Die beiden Gründer des Unternehmens sind international anerkannte Spezialisten auf diesem Gebiet und nutzten ihre gesammelte Expertise in der Kernrezeptorbiologie, Toxikologie, medizinischer Chemie und Molekularbiologie, um die Technologie-Plattform für diese Produkte zu entwickeln.
Mehr Informationen unter: www.indigobiosciences.com
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RARgamma (human) Reporter Assay Kit
Artikelnummer: IB-IB02001
This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the human retinoic acid receptor gamma (NR1B3), a ligand-dependent transcription factor commonly referred to as RARG or RARgamma. INDIGO's reporter cells include the luciferase...
| Schlagworte: | RARG, NR1B3, RAR-gamma, Retinoic acid receptor gamma, Nuclear receptor subfamily 1 group B member 3 |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
ab 1.448,00 €
RXRbeta (human) Reporter Assay Kit
Artikelnummer: IB-IB00811
This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the human retinoid X receptor beta (NR2B2), a ligand-dependent transcription factor commonly referred to as RXRB or RXRbeta. INDIGO's reporter cells include the luciferase reporter...
| Schlagworte: | RXRB, NR2B2, Retinoid X receptor beta, Retinoic acid receptor RXR-beta, Nuclear receptor subfamily 2 group B member 2 |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
ab 1.448,00 €
RXRgamma (human) Reporter Assay Kit
Artikelnummer: IB-IB00821
This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the human retinoid X receptor gamma (NR2B3), a ligand-dependent transcription factor commonly referred to as RXRG or RXRgamma. INDIGO's reporter cells include the luciferase reporter...
| Schlagworte: | RXRG, NR2B3, Retinoid X receptor gamma, Retinoic acid receptor RXR-gamma, Nuclear receptor subfamily 2 group B member 3 |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
ab 1.448,00 €
RXRalpha (human) Reporter Assay Kit
Artikelnummer: IB-IB00801
This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the human retinoid X receptor alpha (NR2B1), a ligand-dependent transcription factor commonly referred to as RXRA or RXRalpha. INDIGO's reporter cells include the luciferase reporter...
| Schlagworte: | RXRA, NR2B1, Retinoid X receptor alpha, Retinoic acid receptor RXR-alpha, Nuclear receptor subfamily 2 group B member 1 |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
ab 1.448,00 €
PPAR (human) Reporter Assays Panel
Artikelnummer: IB-IB00131-32P
INDIGO's panel of PPAR reporter assays utilizes non-human mammalian cells engineered to express human peroxisome proliferator-activated receptors: PPARalpha (NR1C1), PPARdelta (NR1C2), or PPARgamma (NR1C3), all ligand-dependent transcription factors that are commonly referred to as PPARalpha, PPARdelta and...
| Schlagworte: | PPARalpha (NR1C1), PPARdelta (NR1C2), PPARgamma (NR1C3) |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
1.894,00 €
LXRbeta (human) Reporter Assay Kit
Artikelnummer: IB-IB00302
This nuclear receptor assay system utilizes proprietary non-human mammalian cells engineered to provide constitutive, high-level expression of human liver X receptor beta (NR1H2), a ligand-dependent transcription factor commonly referred to as LXRbeta. INDIGO's reporter cells include the luciferase reporter gene...
| Schlagworte: | LXRB, NR1H2, Nuclear receptor NER, Liver X receptor beta, Oxysterols receptor LXR-beta, Ubiquitously-expressed nuclear... |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
3.802,00 €
MR (human) Reporter Assay Kit
Artikelnummer: IB-IB00502
This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive high-level expression of full-length, unmodified human mineralocorticoid receptor (NR3C2), a ligand-dependent transcription factor commonly referred to as MR. INDIGO's reporter cells include the luciferase...
| Schlagworte: | MR, MCR, NR3C2, Mineralocorticoid receptor, Nuclear receptor subfamily 3 group C member 2 |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
3.802,00 €
FXR (human) Reporter Assay Kit
Artikelnummer: IB-IB00602
This nuclear receptor assay system utilizes proprietary non-human mammalian cells engineered to provide constitutive, high-level expression of human farnesoid X receptor (NR1H4), a ligand-dependent transcription factor commonly referred to as FXR. INDIGO's reporter cells include the luciferase reporter gene...
| Schlagworte: | BAR, NR1H4, Bile acid receptor, Farnesol receptor HRR-1, RXR-interacting protein 14, Farnesoid X-activated receptor,... |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
3.802,00 €
PR (human) Reporter Assay Kit
Artikelnummer: IB-IB05002
This nuclear receptor assay system utilizes proprietary human cells engineered to provide constitutive, high-level expression of the full-length human progesterone receptor (NR3C3), a ligand-dependent transcription factor commonly referred to as PR. INDIGO's reporter cells include the luciferase reporter gene...
| Schlagworte: | PR, PGR, NR3C3, Progesterone receptor, Nuclear receptor subfamily 3 group C member 3 |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
3.802,00 €
MR (human) Reporter Assay Kit
Artikelnummer: IB-IB00501-32
This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive high-level expression of full-length, unmodified human mineralocorticoid receptor (NR3C2), a ligand-dependent transcription factor commonly referred to as MR. INDIGO's reporter cells include the luciferase...
| Schlagworte: | MR, MCR, NR3C2, Mineralocorticoid receptor, Nuclear receptor subfamily 3 group C member 2 |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
ab 1.448,00 €
PPARdelta (human) Reporter Assay Kit
Artikelnummer: IB-IB00121
This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the human peroxisome proliferator-activated receptor delta (NR1C2), a ligand-dependent transcription factor commonly referred to as PPARD or PPARdelta. INDIGO's reporter cells include...
| Schlagworte: | NUCI, NUC1, NR1C2, PPARD, PPAR-beta, PPAR-delta, Nuclear hormone receptor 1, Nuclear receptor subfamily 1 group C member... |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
ab 1.448,00 €
FXR (mouse) Reporter Assay Kit
Artikelnummer: IB-M00601-32
This nuclear receptor assay system utilizes proprietary non-human mammalian cells engineered to provide constitutive, high-level expression of human farnesoid X receptor (NR1H4), a ligand-dependent transcription factor commonly referred to as FXR. INDIGO's reporter cells include the luciferase reporter gene...
| Schlagworte: | Bar, Nr1h4, Bile acid receptor, Farnesol receptor HRR-1, RXR-interacting protein 14, Farnesoid X-activated receptor,... |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | mouse |
ab 1.448,00 €