Produkte von Indigo Biosciences

Indigo

Indigo Biosciences, Inc. wurde im Jahr 2005 in State College, PA von Dr. Jack Vanden Heuvel und Dr. Blake Peterson gegründet. Das biowissenschaftliche Unternehmen konzentriert sich auf Produkte und Dienstleistungen im Bereich Kernrezeptoren, die eine wichtige Klasse von therapeutischen Wirkstoffzielen darstellen. Hierbei stellen quantitative Aktivitäts-Assays noch immer eine besondere Herausforderung für die Biotechnologie dar. Die beiden Gründer des Unternehmens sind international anerkannte Spezialisten auf diesem Gebiet und nutzten ihre gesammelte Expertise in der Kernrezeptorbiologie, Toxikologie, medizinischer Chemie und Molekularbiologie, um die Technologie-Plattform für diese Produkte zu entwickeln.

Mehr unter: indigobiosciences.com

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RXRbeta (human) Reporter Assay Kit
RXRbeta (human) Reporter Assay Kit

Artikelnummer: IB-IB00811

This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the human retinoid X receptor beta (NR2B2), a ligand-dependent transcription factor commonly referred to as RXRB or RXRbeta. INDIGO's reporter cells include the luciferase reporter...
Schlagworte: RXRB, NR2B2, Retinoid X receptor beta, Retinoic acid receptor RXR-beta, Nuclear receptor subfamily 2 group B member 2
Anwendung: Functional activity screening
Reaktivität: Human
ab 1.161,00 €
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RXRgamma (human) Reporter Assay Kit
RXRgamma (human) Reporter Assay Kit

Artikelnummer: IB-IB00821

This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the human retinoid X receptor gamma (NR2B3), a ligand-dependent transcription factor commonly referred to as RXRG or RXRgamma. INDIGO's reporter cells include the luciferase reporter...
Schlagworte: RXRG, NR2B3, Retinoid X receptor gamma, Retinoic acid receptor RXR-gamma, Nuclear receptor subfamily 2 group B member 3
Anwendung: Functional activity screening
Reaktivität: Human
ab 1.161,00 €
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RXRalpha (human) Reporter Assay Kit
RXRalpha (human) Reporter Assay Kit

Artikelnummer: IB-IB00801

This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the human retinoid X receptor alpha (NR2B1), a ligand-dependent transcription factor commonly referred to as RXRA or RXRalpha. INDIGO's reporter cells include the luciferase reporter...
Schlagworte: RXRA, NR2B1, Retinoid X receptor alpha, Retinoic acid receptor RXR-alpha, Nuclear receptor subfamily 2 group B member 1
Anwendung: Functional activity screening
Reaktivität: Human
ab 1.161,00 €
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FXR (mouse) Reporter Assay Kit
FXR (mouse) Reporter Assay Kit

Artikelnummer: IB-M00601-32

This nuclear receptor assay system utilizes proprietary non-human mammalian cells engineered to provide constitutive, high-level expression of human farnesoid X receptor (NR1H4), a ligand-dependent transcription factor commonly referred to as FXR. INDIGO's reporter cells include the luciferase reporter gene...
Schlagworte: Bar, Nr1h4, Bile acid receptor, Farnesol receptor HRR-1, RXR-interacting protein 14, Farnesoid X-activated receptor,...
Anwendung: Functional activity screening
Reaktivität: Mouse
ab 1.161,00 €
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PPAR (human) Reporter Assays Panel
PPAR (human) Reporter Assays Panel

Artikelnummer: IB-IB00131-32P

INDIGO's panel of PPAR reporter assays utilizes non-human mammalian cells engineered to express human peroxisome proliferator-activated receptors: PPARalpha (NR1C1), PPARdelta (NR1C2), or PPARgamma (NR1C3), all ligand-dependent transcription factors that are commonly referred to as PPARalpha, PPARdelta and...
Schlagworte: PPARalpha (NR1C1), PPARdelta (NR1C2), PPARgamma (NR1C3)
Anwendung: Functional activity screening
Reaktivität: Human
1.539,00 €
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MR (human) Reporter Assay Kit
MR (human) Reporter Assay Kit

Artikelnummer: IB-IB00502

This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive high-level expression of full-length, unmodified human mineralocorticoid receptor (NR3C2), a ligand-dependent transcription factor commonly referred to as MR. INDIGO's reporter cells include the luciferase...
Schlagworte: MR, MCR, NR3C2, Mineralocorticoid receptor, Nuclear receptor subfamily 3 group C member 2
Anwendung: Functional activity screening
Reaktivität: Human
3.065,00 €
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FXR (human) Reporter Assay Kit
FXR (human) Reporter Assay Kit

Artikelnummer: IB-IB00602

This nuclear receptor assay system utilizes proprietary non-human mammalian cells engineered to provide constitutive, high-level expression of human farnesoid X receptor (NR1H4), a ligand-dependent transcription factor commonly referred to as FXR. INDIGO's reporter cells include the luciferase reporter gene...
Schlagworte: BAR, NR1H4, Bile acid receptor, Farnesol receptor HRR-1, RXR-interacting protein 14, Farnesoid X-activated receptor,...
Anwendung: Functional activity screening
Reaktivität: Human
3.065,00 €
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PR (human) Reporter Assay Kit
PR (human) Reporter Assay Kit

Artikelnummer: IB-IB05002

This nuclear receptor assay system utilizes proprietary human cells engineered to provide constitutive, high-level expression of the full-length human progesterone receptor (NR3C3), a ligand-dependent transcription factor commonly referred to as PR. INDIGO's reporter cells include the luciferase reporter gene...
Schlagworte: PR, PGR, NR3C3, Progesterone receptor, Nuclear receptor subfamily 3 group C member 3
Anwendung: Functional activity screening
Reaktivität: Human
3.065,00 €
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ERbeta (human) Reporter Assay Kit
ERbeta (human) Reporter Assay Kit

Artikelnummer: IB-IB00411

This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the full-length human estrogen receptor 2 (NR3A2), a ligand-dependent transcription factor commonly referred to as ERbeta. INDIGO's reporter cells include the luciferase reporter gene...
Schlagworte: ESR2, ESTRB, ER-beta, Estrogen receptor beta, Nuclear receptor subfamily 3 group A member 2
Anwendung: Functional activity screening
Reaktivität: Human
ab 1.161,00 €
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AhR (human) Assay Kit
AhR (human) Assay Kit

Artikelnummer: IB-IB06001

INDIGO's Aryl Hydrocarbon Receptor (AhR) Reporter Cells include the luciferase reporter gene functionally linked to an AhR-responsive promoter. Thus, quantifying changes in luciferase expression in the treated reporter cells provides a sensitive surrogate measure of the changes in AhR activity. The principle...
Schlagworte: Aryl Hydrocarbon Receptor (human) Assay Kit, AHR, AhR, BHLHE76, bHLHe76, Ah receptor, Aryl hydrocarbon receptor, Class E...
Anwendung: Functional activity screening
ab 1.161,00 €
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PPARdelta (human) Reporter Assay Kit
PPARdelta (human) Reporter Assay Kit

Artikelnummer: IB-IB00121

This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the human peroxisome proliferator-activated receptor delta (NR1C2), a ligand-dependent transcription factor commonly referred to as PPARD or PPARdelta. INDIGO's reporter cells include...
Schlagworte: NUCI, NUC1, NR1C2, PPARD, PPAR-beta, PPAR-delta, Nuclear hormone receptor 1, Nuclear receptor subfamily 1 group C member...
Anwendung: Functional activity screening
Reaktivität: Human
ab 1.161,00 €
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GR (human) Reporter Assay Kit
GR (human) Reporter Assay Kit

Artikelnummer: IB-IB00202

This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive high-level expression of full-length, unmodified human glucocorticoid receptor (NR3C1), a ligand-dependent transcription factor, commonly referred to as GR. INDIGO's reporter cells include the luciferase...
Schlagworte: GR, GRL, NR3C1, Glucocorticoid receptor, Nuclear receptor subfamily 3 group C member 1
Anwendung: Functional activity screening
Reaktivität: Human
3.065,00 €
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