Produkte von AdipoGen Life Sciences
AdipoGen Life Sciences verbindet Immunologie und Metabolismus. Die AdipoGen-Zentrale befindet sich in San Diego, USA mit einem Produktionslabor in der Schweiz. Hoch qualifizierte Wissenschaftler*innen entwickeln dort neue Produkte für den Life Science-Markt in den Bereichen Krebs, Immunologie, Entzündung (der Experte im Bereich Inflammasom-Forschung), Metabolisches Syndrom (Diabetes, Fettleibigkeit), Stammzellen und Neurodegeneration. Der Schwerpunkt liegt auf innovativen und fortschrittlichen ELISA-Kits. Zusätzlich zu den Antikörper- und Protein-Einrichtungen besitzt AdipoGen auch chemische Laboratorien für die Entwicklung neuer und innovativer Biochemikalien.
Mehr Informationen unter: www.adipogen.com
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YM-254890
Artikelnummer: AG-CN2-0509-MC05
Off-white solid. Soluble in DMSO (10mg/ml). Cyclic depsipeptide composed of unique amino acids differing from normal amino acids, Membrane permeable, potent and selective Galphaq family inhibitor, Inhibits the signal transduction of Galphaq, Galpha11 and Galpha14 (IC50=0.095&mu,M) by blocking the exchange of GDP for...
| Schlagworte: | QS 3666A |
| Anwendung: | G alpha q family inhibitor |
| CAS | 568580-02-9 |
| MW: | 960,1 D |
ab 220,00 €
Ganglioside GM1 . sodium salt (bovine brain)
Artikelnummer: AG-CN2-9000-M001
Isolated from bovine brain. Gangliosides are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell...
| Schlagworte: | GM1 . Na, Monosialoganglioside GM1 . Na |
| Anwendung: | Acidic glycosphingolipid |
| CAS | 37758-47-7 |
| MW: | 1545,8 D |
ab 99,00 €
Forskolin
Artikelnummer: AG-CN2-0089-M050
Isolated from Coleus forskohlii. Potent, cell permeable adenylyl cyclase activator. Increases intracellular cAMP levels. Widely used tool to investigate cAMP as a second messenger. Inotropic and antihypertensive. Smooth muscle relaxant/vasodilator. Glucose transporter inhibitor. Platelet aggregation inhibitor....
| Schlagworte: | Boforsin, Colforsin, Coleonol, NSC 357088, NSC 375489 |
| Anwendung: | Cell permeable adenylate cyclase activator |
| CAS | 66575-29-9 |
| MW: | 410,5 D |
ab 22,00 €
Staurosporine
Artikelnummer: AG-CN2-0022-M001
Isolated from Streptomyces spiralis. Antibiotic. Antifungal and anti-yeast activity. Inhibits platelet aggregation induced by collagen or ADP. Has no effect on thrombin-induced platelet aggregation. Potent, cell permeable, reversible, ATP-competitive and broad spectrum inhibitor of protein kinases. Inhibits protein...
| Schlagworte: | Antibiotic AM2282, Antibiotic 230, CCRIS 3272 |
| Anwendung: | Protein kinase inhibitor, Apoptosis inducer |
| CAS | 62996-74-1 |
| MW: | 466,5 D |
ab 33,00 €
COVID-19 Forschung
SARS-CoV-2 Inhibitor Screening Kit
Artikelnummer: AG-48B-0001-KI01
To screen compounds that inhibit the binding of the viral protein SARS-CoV-2 Spike Protein (RBD) to its human receptor ACE2. Coronaviruses (CoVs) are enveloped non-segmented positive-sense single-stranded RNA viruses and can infect respiratory, gastrointestinal, hepatic and central nervous system of human and many...
| Schlagworte: | COVID-19 Inhibitor Screening Kit, 2019-nCoV Inhibitor Screening Kit, 2019-nCoV Spike Protein S1 (RBD)/ACE2 Inhibitor... |
| Anwendung: | Compound Screening |
| Spezies-Reaktivität: | human |
737,00 €
Anti-LAG-3 (human), clone 17B4), ATTO 647N conjugated
Artikelnummer: AG-20B-0012TS-T100
Recognizes human LAG-3. Liquid. In PBS containing 0.02% sodium azide. Lymphocyte activation gene 3 (LAG-3, CD223) plays an important role in negatively regulating T cell proliferation, function, and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely...
| Schlagworte: | Lymphocyte Activation Gene-3, FDC Protein, CD223 |
| Anwendung: | FC, ICC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
451,00 €
Empagliflozin
Artikelnummer: AG-CR1-3619-M010
White solid. Soluble in DMSO. Slightly soluble in water or ethanol. Antidiabetic agent, Potent and selective sodium glucose co-transporter 2 (SGLT-2) inhibitor. >,300-fold selectivity over SGLT-1, 4, 5 and 6, SGLT-2 is found almost exclusively in the proximal tubules of nephronic components in kidneys. Inhibition...
| Schlagworte: | Jardiance, BI-10773 |
| Anwendung: | Antidiabetic agent, SGLT2 inhibitor |
| CAS | 864070-44-0 |
| MW: | 450,9 D |
ab 77,00 €
Resveratrol
Artikelnummer: AG-CN2-0033-M050
Isolated from Polygonum cuspidatum. Its effects are numerous and include anti-cancer, anti-inflammatory, anti-fungal and has other beneficial cardiovascular effects.
| Schlagworte: | trans-3,4',5-Trihydroxystilbene, trans-Resveratrol, (E)-Resveratrol, 3,4',5-Stilbenetriol |
| Anwendung: | Antioxidant, Adipogenesis inhibitor, Chemopreventive |
| CAS | 501-36-0 |
| MW: | 228,2 D |
ab 33,00 €
JC-1
Artikelnummer: AG-CR1-3568-M001
5 x 1 mg. The membrane-permeant dual-emission potential-sensitive JC-1 dye is widely used in apoptosis studies to monitor mitochondrial health by flow cytometry, fluorescence microscopy and in microplate-based fluorescent assays. JC-1 dye can be used as an indicator of mitochondrial membrane potential in a variety...
| Schlagworte: | 5,5',6,6'-Tetrachloro-1,1',3,3'-tetraethylbenzimidazolylcarbocyanine iodide |
| Anwendung: | Mitochondrial membrane potential indicator, FC |
| CAS | 3520-43-2 |
| MW: | 652,2 D |
ab 66,00 €
MTSSL
Artikelnummer: AG-CR1-3573-M050
Highly reactive, thiol-specific spin-label. Specific conformational probe of thiol site structure by its minimal rotational freedom and distance from the covalent disulfide linkage to the macromolecule under study. Used to label cysteine residues in proteins (site-directed labeling, SDS-labeling). Allows protein...
| Schlagworte: | Mts-SL, MTSL, (1-Oxyl-2,2,5,5-tetramethylpyrroline-3- methyl)methanethiosulfonate, Otmpmms |
| Anwendung: | Protein labeling, Thiol-specific spin-label |
| Wirt: | Synthetic |
| CAS | 81213-52-7 |
| MW: | 264,3 D |
ab 83,00 €
G418, sulfate
Artikelnummer: AG-CN2-0030-G005
Isolated from Micromonospora rhodorangea. Antibiotic. Cytotoxic to prokaryotic and eukaryotic cells by inhibiting the protein synthesis. Apoptosis inducer. Widely employed in the selection of eukaryotic expression vectors, in combination with either aminoglycoside phosphotransferase 3' or APH II. Antiviral. Assay:...
| Schlagworte: | Geneticin, Antibiotic G418, BRN 1669188 |
| Anwendung: | Apoptosis inducer |
| CAS | 108321-42-2 |
ab 33,00 €
Antibiotic PF 1052
Artikelnummer: BVT-0338-M001
Antibiotic, Antibacterial, antifungal and phytotoxic. Isolated from Phoma sp.
| Schlagworte: | (E)-5-(sec-Butyl)-3-((2-(2,3-dimethyloxiran-2-yl)-6,8-dimethyl-1,2,4a,5,6,7,8,8a-octahydronaphthalen-1-yl)(hydroxy)methyle... |
| Anwendung: | Bioassays |
| CAS | 147317-15-5 |
| MW: | 429,6 D |
ab 120,00 €