Produkte von AdipoGen Life Sciences
AdipoGen Life Sciences verbindet Immunologie und Metabolismus. Die AdipoGen-Zentrale befindet sich in San Diego, USA mit einem Produktionslabor in der Schweiz. Hoch qualifizierte Wissenschaftler*innen entwickeln dort neue Produkte für den Life Science-Markt in den Bereichen Krebs, Immunologie, Entzündung (der Experte im Bereich Inflammasom-Forschung), Metabolisches Syndrom (Diabetes, Fettleibigkeit), Stammzellen und Neurodegeneration. Der Schwerpunkt liegt auf innovativen und fortschrittlichen ELISA-Kits. Zusätzlich zu den Antikörper- und Protein-Einrichtungen besitzt AdipoGen auch chemische Laboratorien für die Entwicklung neuer und innovativer Biochemikalien.
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AOH1996
Artikelnummer: AG-CR1-3553-M005
AOH1996 is an orally available and metabolically stable small molecule PCNA inhibitor, which selectively kills cancer cells, with a median concentration of about 300 nM for 50% growth inhibition. AOH1996 was not significantly toxic to non-malignant cells, even up to 10 µM. AOH1996 enhances the interaction between...
| Schlagworte: | NSC789796, N-(2-((2-(3-Methoxyphenoxy)phenyl)amino)-2-oxoethyl)-1-naphthamide |
| CAS | 2089314-64-5 |
| MW: | 426.5 D |
ab 132,00 €
Nigericin, sodium salt
Artikelnummer: AG-CN2-0020-M005
Isolated from Streptomyces hygroscopicus. Antibiotic. High affinity ionophore for monovalent cations such as H, K, Na, Pb2. Shows antibacterial (Gram-positive), antifungal, antitumor and antiviral activity. Disrupts membrane potential and Golgi apparatus in mitochondria. NLRP3/NALP3 activator. Signals through...
| Schlagworte: | Antibiotic K 178, Helexin C, Polyetherin A, BRN 1696755, Azalomycin M, Antibiotic X-464 |
| Anwendung: | Ionophore |
| CAS | 28643-80-3 |
ab 66,00 €
YM-254890
Artikelnummer: AG-CN2-0509-MC05
Off-white solid. Soluble in DMSO (10mg/ml). Cyclic depsipeptide composed of unique amino acids differing from normal amino acids, Membrane permeable, potent and selective Galphaq family inhibitor, Inhibits the signal transduction of Galphaq, Galpha11 and Galpha14 (IC50=0.095&mu,M) by blocking the exchange of GDP for...
| Schlagworte: | QS 3666A |
| Anwendung: | G alpha q family inhibitor |
| CAS | 568580-02-9 |
| MW: | 960,1 D |
ab 220,00 €
Fc (LALA-PG)-KIH (human) IgG1 Control (rec.)
Artikelnummer: AG-35B-0018-C050
Negative control in experiments with recombinant proteins fused to human IgG1 Fc (LALA-PG)-KIH (Knobs-into-Holes) (e.g. Prod. No. AG-40B-0248). This protein is not an appropriate negative control for other standard Fc protein constructs. The protein Fc (LALA-PG)-KIH (human) IgG1 Control (rec.) is produced by using...
| Schlagworte: | Ig gamma-1 chain C region, Ig gamma-1 chain C region EU, Ig gamma-1 chain C region NIE, Ig gamma-1 chain C region KOL,... |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 28 kD |
341,00 €
IL-38 (human) (rec.) (His)
Artikelnummer: AG-40A-0191Y-3010
IL-38 (IL-1F10) mRNA is expressed in heart, placenta, fetal liver, spleen, thymus and tonsil. The expression in a variety of immune tissues and similarity to IL-1Ra suggest a role of IL-1F10 in the inflammatory response. It has been reported that removal of the N-terminus domain of the interleukins of the IL-1F...
| Schlagworte: | FIL1T, IL-38, FKSG75, IL-1HY2, IL-1F10, IL-1 theta, FIL1 theta, Interleukin-38, Interleukin-1 HY2, Interleukin-1 theta,... |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 18 kD |
ab 264,00 €
Fc (LALA-PG)-KIH (human):GDF15 (mouse) (rec.)
Artikelnummer: AG-40B-0245-C050
Growth and differentiation factor 15 (GDF15, also known as macrophage inhibitory cytokine-1 (MIC-1)), is a member of the transforming growth factor (TGF)-beta superfamily and was initially identified in activated macrophages. GDF15 acts through a recently identified receptor called Glial-derived Neurotrophic Factor...
| Schlagworte: | MIC-1, GDF-15, Growth/differentiation factor 15, Macrophage inhibitory cytokine 1 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 4530 kD |
440,00 €
Fc (LALA-PG)-KIH (human):Irisin (monomeric) (rec.)
Artikelnummer: AG-40B-0246-C050
Irisin is a recently described exercise-induced hormone secreted by skeletal muscle in mice and humans. Irisin activates beige fat cells (beige cells have a gene expression pattern distinct from either white or brown fat and are preferentially sensitive to the polypeptide hormone Irisin). Irisin is cleaved from the...
| Schlagworte: | FNDC5, FRCP2 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 5530 kD |
440,00 €
IL-23 (mouse):Fc (LALA-PG)-KIH (human) (rec.)
Artikelnummer: AG-40B-0248-C050
Interleukin-12 (IL-12) family members are heterodimer glycoproteins, composed of two covalently linked subunits, alpha and beta chains. The alpha-subunit consists of IL-23p19, IL-27p28, and IL-12p35, and the beta-subunit includes IL-12p40 and Epstein-Barr virus-induced gene (Ebi3). IL-12 members bind to cognate...
| Schlagworte: | Il23a, IL-23-A, IL-23p19, IL-23 subunit alpha, Interleukin-23 subunit p19, Interleukin-23 subunit alpha |
| Exprimiert in: | Hamster cells |
| Ursprungsart: | mouse |
| MW: | 7555 kD |
440,00 €
IL-27 (mouse):Fc (LALA-PG)-KIH (human) (rec.)
Artikelnummer: AG-40B-0249-C050
Interleukin-12 (IL-12) family members are heterodimer glycoproteins, composed of two covalently linked subunits, alpha and beta chains. The alpha-subunit consists of IL-23p19, IL-27p28, and IL-12p35, and the beta-subunit includes IL-12p40 and Epstein-Barr virus-induced gene (Ebi3). IL-12 members bind to cognate...
| Schlagworte: | p28, Il27, Il27a, IL27-A, IL-27-A, IL-27 subunit alpha, Interleukin-27 subunit alpha |
| Exprimiert in: | Hamster cells |
| Ursprungsart: | mouse |
| MW: | 6260 kD |
440,00 €
Isthmin-1 (human) ELISA Kit
Artikelnummer: AG-45B-0032-KI01
Isthmin-1 (ISM1) was first identified as a gene expressed in the Xenopus midbrain-hindbrain organizer called the isthmus, with a proposed role during early brain development. Isthmin-1 encodes a predicted ~50-kDa protein containing a signal peptide, a thrombospondin domain and an adhesion-associated domain....
| Schlagworte: | ISM1, C20orf82, Isthmin-1 |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
550,00 €
Spilanthol
Artikelnummer: AG-CN2-0543-M005
Spilanthol is a natural non-toxic compound. It is a sesquiterpene lactone and has been traditionally used in folk medicine. It has sensory properties (pungency, tingling, numbing, mouth-watering) and is an excellent stable model compound for sensory/chemoreception studies like pellitorine and a biological analog of...
| Schlagworte: | Affinin, (2E,6Z,8E)-N-Isobutyldeca-2,6,8-trienamide |
| CAS | 25394-57-4 |
| MW: | 221,3 D |
297,00 €
Inosine
Artikelnummer: AG-CR1-3554-G001
Inosine, an intermediate in purine metabolism, consists of hypoxanthine and ribose. It is an inert purine nucleoside formed by breakdown of adenosine (deamination, known as A-to-I editing that occurs in tRNA and mRNA) or also is generated by the action of 5'-nucleotidase on inosine monophosphate (IMP). Inosine has...
| Schlagworte: | 9-beta-D-Ribofuranosylhypoxanthine, NSC 20262, Hypoxanthine 9-beta-D-ribofuranoside |
| CAS | 58-63-9 |
| MW: | 268,2 D |
ab 22,00 €