Zu "209783-80-2" wurden 4 Artikel gefunden!
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MS-275
Artikelnummer: Cay13284-1
MS-275 is an inhibitor of histone deacetylases (HDACs) that preferentially inhibits HDAC1 (IC50 = 300 nM) over HDAC3 (IC50 = 8 µM). However, it does not inhibit HDAC8 (IC50 > 100 µM). MS-275 induces cyclin-dependent kinase inhibitor 1A (p21/CIP1/WAF1), slowing cell growth, differentiation, and tumor development in...
| Schlagworte: | Entinostat, SNDX 275, N-[[4-[[(2-aminophenyl)amino]carbonyl]phenyl]methyl]-carbamic acid, 3-pyridinylmethyl ester |
| Anwendung: | HDAC inhibitor |
| CAS | 209783-80-2 |
| MW: | 376.4 D |
ab 28,00 €
MS-275
Artikelnummer: AG-CR1-0032-M001
HDAC 1 inhibitor, Antitumor compound, Antiproliferative, TGF-beta type II receptor inducer, Apoptosis inducer, Anti-inflammatory, Angiogenesis inhibitor, Review.
| Schlagworte: | N-(2-Aminophenyl)-4-[N-(pyridine-3-ylmethoxy-carbonyl)aminomethyl]benzamide, MS-27-275 |
| Anwendung: | HDAC 1 inhibitor |
| CAS | 209783-80-2 |
| MW: | 376,4 D |
ab 17,00 €
MS-275 (Entinostat, SNDX-275)
Artikelnummer: M4693-15A.25
MS-275 is a synthetic benzamide derivative that inhibited partially purified human histone deacetylase (HDA) with an IC50 of 2uM and induced hyperacetylation of nuclear histones in tumor cell lines. MS-275 inhibited the proliferation of various human tumor cell lines such as A2780, Calu-3, HL-60, and K562 (IC50...
| CAS | 209783-80-2 |
| MW: | 376.41 |
256,00 €
Entinostat
Artikelnummer: LKT-E5477.1
A synthetic benzamide derivative with potential antineoplastic activity. Entinostat binds to and inhibits histone deacetylase, an enzyme that regulates chromatin structure and gene transcription.
| Schlagworte: | SNDX-275, MS-275 |
| Anwendung: | HDAC inhibitor |
| CAS | 209783-80-2 |
| MW: | 376,41 D |
ab 60,00 €
