Zu "183319-69-9" wurden 5 Artikel gefunden!
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Erlotinib Monohydrochloride
Artikelnummer: LKT-E6846.10
The hydrochloride salt of a quinazoline derivative with anti-neoplastic properties. Competes with ATP, Erlotinib reversibly binds to EGFR tyroside kinase which blocks the signal transduction events and tumorigenic events associated with EGFR activation.
| CAS | 183319-69-9 |
| MW: | 429,9 D |
ab 69,00 €
Erlotinib hydrochloride
Artikelnummer: SYN-1039-M001
Soluble in DMSO. Slightly soluble ( 1000-fold more sensitive for EGFR than for c-Src or v-Abl. Target: EGFR , Kinase Group: RTK , Substrate: Tyrosine
| Schlagworte: | OSI774, CP-358774, Tarceva, NSC718781 |
| Anwendung: | EGFR inhibitor |
| CAS | 183319-69-9 |
| MW: | 429,9 D |
ab 66,00 €
Erlotinib Hydrochloride
Artikelnummer: E3452-75.1
Inhibitor of the epidermal growth factor receptor tyrosine kinase, which is highly expressed and occasionally mutated in various forms of cancer. Erlotinib binds reversibly to the ATP binding site of the receptor. Solubility: Soluble in DMSO at 18mg/ml with warming, very poorly soluble in ethanol, very poorly...
| CAS | 183319-69-9 |
| MW: | 429.90 |
ab 190,00 €
Erlotinib, Hydrochloride Salt (Tarceva, CP-358774,...
Artikelnummer: LC-E-4007_100g
Soluble in DMSO at 18 mg/mL with warming, very poorly soluble in ethanol, very poorly soluble in water, maximum solubility in plain water is estimated to be about 5-20 µM, buffers, serum, or other additives may increase or decrease the aqueous solubility
| Anwendung: | EGFR inhibitor |
| CAS | 183319-69-9 |
| MW: | 429,9 D |
ab 80,00 €
Erlotinib (hydrochloride)
Artikelnummer: Cay35517-1
Erlotinib is an EGFR inhibitor (Ki = 2.7 nM). It is greater than 1,000-fold selective for EGFR over Src and Abl at 0.1 µM. Erlotinib induces caspase-3 and -7 activity in NCI H358 non-small cell lung cancer (NSCLC) cells when used at a concentration of 1 µM. Erlotinib (25 mg/kg) reduces EGF-induced EGFR...
| Schlagworte: | CP 358,774, NSC 718781, OSI-774, N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine, monohydrochloride |
| Anwendung: | EGFR tyrosine kinase inhibitor |
| CAS | 183319-69-9 |
| MW: | 429.9 D |
ab 69,00 €
