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Tadalafil
Artikelnummer: Cay14024-10
Tadalafil is a potent inhibitor of phosphodiesterase 5 (PDE5, IC50 = 1.2 nM). It is selective for PDE5 over PDE1-4 and 7-10 (IC50s = 9.2-280 µM), however, it does also inhibit PDE11 (IC50 = 11 nM). In vivo, tadalafil (10 mg/kg) decreases production of the proinflammatory cytokines TNF-alpha, IL-1beta, and IL-6 and...
| Schlagworte: | (6R)-6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12aR-hexahydro-2-methyl-pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione |
| Anwendung: | Phosphodiesterase (PDE) V inhibitor |
| CAS | 171596-29-5 |
| MW: | 389.4 D |
ab 60,00 €
Tadalafil
Artikelnummer: CDX-T0455-M050
White to beige powder. Soluble in DMSO (20mg/ml) or DMF (25mg/ml). Chemical. CAS: 171596-29-5. Formula: C22H19N3O4. MW: 389.40. Tadalafil is a potent long-acting and selective inhibitor of the cGMP specific phosphodiesterase 5 (PDE5, IC50 = 1.2 nM). It is selective for PDE5 over PDE1-4 and 7-10 (IC50s = 9.2-280 µM),...
| Schlagworte: | GF196960, (6R,12aR)-6-(1,3-Benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methylpyrazino[1,2:1,6]pyrido[3,4-b]indole-1,4-dione |
| CAS | 171596-29-5 |
| MW: | 389,40 D |
ab 85,00 €
