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XL388
Artikelnummer: Cay20237-5
XL388 is an orally bioavailable and ATP-competitive inhibitor of mammalian target of rapamycin (mTOR, IC50 = 9.9 nM). It is selective for mTOR over a panel of more than 140 kinases, including various PI3Ks (IC50s = >3,000 nM). It inhibits mTOR complex 1 (mTORC1) and mTORC2 in vitro (IC50s = 8 and 166 nM,...
| Schlagworte: | [7-(6-amino-3-pyridinyl)-2,3-dihydro-1,4-benzoxazepin-4(5H)-yl][3-fluoro-2-methyl-4-(methylsulfonyl)phenyl]-methanone |
| Anwendung: | mTOR inhibitor |
| CAS | 1251156-08-7 |
| MW: | 455.5 D |
ab 163,00 €
XL-388
Artikelnummer: SYN-1186-M001
Soluble in DMSO. XL388 is a novel class of highly potent, selective, ATP-competitive, and orally bioavailable inhibitors of the mammalian target of rapamycin (mTOR) with an IC(50) of 9.9nM.
| Schlagworte: | XL-388 |
| Anwendung: | mTOR inhibitor |
| CAS | 1251156-08-7 |
| MW: | 455,5 D |
ab 205,00 €
