Zu "1224844-38-5" wurden 4 Artikel gefunden!
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INK128
Artikelnummer: Cay11811-1
INK128 is an inhibitor of TORC1/2, acting as an ATP-dependent inhibitor of mTOR kinase (IC50 = 1 nM). It blocks the phosphorylation of downstream substrates of both TORC1 and TORC2. INK128 interferes with the growth of cell lines which are resistant to rapamycin and pan-PI3K inhibitors. Moreover, daily, oral...
| Schlagworte: | MLN0128, 3-(2-amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
| Anwendung: | TORC1/2 inhibitor |
| CAS | 1224844-38-5 |
| MW: | 309.3 D |
ab 42,00 €
INK128
Artikelnummer: LKT-I5440.1
INK128, also known as MLN0128, is a TORC1/2 inhibitor, is also an orally bioavailable inhibitor of raptor-mTOR (TOR complex 1 or TORC1) and rictor-mTOR (TOR complex 2 or TORC2) with potential antineoplastic activity. TORC1/2 inhibitor INK128 binds to and inhibits both TORC1 and TORC2 complexes of mTOR, which may...
| Schlagworte: | MLN-0128, MLN0128 |
| Anwendung: | TORC1/2 inhibitor |
| CAS | 1224844-38-5 |
| MW: | 309.33 D |
ab 95,00 €
MLN-0128
Artikelnummer: SYN-1157-M001
Soluble in DMSO or ethanol. MLN0128 is a potent and selective mTOR inhibitor with an IC(50) of 1nM, >200-fold less potent to class I PI3K isoforms, superior in blocking mTORC1/2 and sensitive to pro-invasion genes (vs Rapamycin).
| Schlagworte: | MLN-0128, INK-128 |
| Anwendung: | mTOR inhibitor |
| CAS | 1224844-38-5 |
| MW: | 309,3 D |
ab 125,00 €
INK128, Free Base (MLN-0128, Sapanisertib, CAS...
Artikelnummer: LC-I-3344_100mg
Soluble in DMSO
| Schlagworte: | MLN0128, 3-(2-amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
| Anwendung: | TORC1/2 inhibitor |
| CAS | 1224844-38-5 |
| MW: | 309,33 D |
ab 216,00 €
