Zu "biosimilar" wurden 173 Artikel gefunden!
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Anti-PD-1 (Nivolumab Biosimilar Biosimilar In Vivo...
Artikelnummer: G-IVMB0210.500
Endotoxin level: < 1.0 EU/mg as determined by the LAL method. Protein function: Inhibitory receptor on antigen activated T-cells that plays a critical role in induction and maintenance of immune tolerance to self (PubMed:21276005). Delivers inhibitory signals upon binding to ligands CD274/PDCD1L1 and CD273/PDCD1LG2...
| Schlagworte: | Anti-hPD-1, Anti-CD279, Anti-Protein PD-1, Anti-Programmed cell death protein 1 |
| Anwendung: | WB, FA, FC, IHC |
| Wirt: | Human |
| Spezies-Reaktivität: | human, Cynomolgus monkey |
620,00 €
Anti-5T4 (H8 Biosimilar Antibody)
Artikelnummer: G-HDBS0137.100
Protein function: May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. [The UniProt Consortium]
| Schlagworte: | Anti-5T4, Anti-M6P1, Anti-TPBG, Anti-WAIF1, Anti-5T4 oncofetal antigen, Anti-Trophoblast glycoprotein, Anti-5T4... |
| Anwendung: | ELISA, FC |
| Wirt: | Human |
| Spezies-Reaktivität: | human |
399,00 €
Anti-OX40L (Oxelumab Biosimilar In Vivo Antibody (Fc...
Artikelnummer: G-IVMB0212.500
Endotoxin level: < 1.0 EU/mg as determined by the LAL method. Protein function: Cytokine that binds to TNFRSF4. Co-stimulates T-cell proliferation and cytokine production. [The UniProt Consortium]
| Schlagworte: | Anti-TXGP1, Anti-OX40L, Anti-CD252, Anti-TNFSF4, Anti-OX40 ligand, Anti-Glycoprotein Gp34, Anti-TAX... |
| Anwendung: | WB, FA, FC |
| Wirt: | Human |
| Spezies-Reaktivität: | human |
620,00 €
Anti-IL-6 (Sarilumab Biosimilar In Vivo Antibody (Fc...
Artikelnummer: G-IVMB0220.500
Endotoxin level: < 1.0 EU/mg as determined by the LAL method. Protein function: Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway...
| Schlagworte: | Anti-CDF, Anti-IL-6, Anti-IFNB2, Anti-BSF-2, Anti-IFN-beta-2, Anti-Interleukin-6, Anti-Interferon beta-2, Anti-Hybridoma... |
| Anwendung: | WB, ELISA, FA, FC, IHC, Neutr., WB |
| Wirt: | Human |
| Spezies-Reaktivität: | human |
620,00 €
Anti-EGFR (Cetuximab Biosimilar In Vivo Antibody (Fc...
Artikelnummer: G-IVMB0240.500
Endotoxin level: < 1.0 EU/mg as determined by the LAL method. Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses (PubMed:2790960, PubMed:10805725, PubMed:27153536). Known ligands...
| Schlagworte: | Anti-ERBB, EC=2.7.10.1, Anti-Proto-oncogene c-ErbB-1, Anti-Epidermal growth factor receptor, Anti-Receptor... |
| Anwendung: | WB, CyTOF, FC |
| Wirt: | Human |
| Spezies-Reaktivität: | human |
416,00 €
Anti-CD20 (Rituximab Biosimilar In Vivo Antibody (Fc...
Artikelnummer: G-IVMB0243.500
Endotoxin level: < 1.0 EU/mg as determined by the LAL method. Protein function: B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes (PubMed:3925015, PubMed:7684739, PubMed:12920111)....
| Schlagworte: | Anti-Bp35, Anti-CD20, Anti-MS4A1, Anti-B-lymphocyte antigen CD20, Anti-B-lymphocyte surface antigen B1, Anti-Leukocyte... |
| Anwendung: | FC |
| Wirt: | Human |
| Spezies-Reaktivität: | human, Rhesus monkey, Cynomolgus monkey |
620,00 €
Anti-HER-2 (Trastuzumab Biosimilar In Vivo Antibody (Fc...
Artikelnummer: G-IVMB0216.500
Endotoxin level: < 1.0 EU/mg as determined by the LAL method. Protein function: Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with...
| Schlagworte: | Anti-HER2, Anti-ERBB2, Anti-CD340, Anti-MLN 19, Anti-p185erbB2, EC=2.7.10.1, Anti-Proto-oncogene Neu, Anti-Proto-oncogene... |
| Anwendung: | CyTOF, ELISA, FC, IHC |
| Wirt: | Human |
| Spezies-Reaktivität: | human |
620,00 €
Anti-CTLA-4 (Ipilimumab Biosimilar In Vivo Antibody (Fc...
Artikelnummer: G-IVMB0218.500
Endotoxin level: < 1.0 EU/mg as determined by the LAL method. Protein function: Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor...
| Schlagworte: | Anti-CTLA4, Anti-CD152, Anti-CTLA-4, Anti-Cytotoxic T-lymphocyte protein 4, Anti-Cytotoxic T-lymphocyte-associated antigen 4 |
| Anwendung: | WB, CyTOF, ELISA, FC |
| Wirt: | Human |
| Spezies-Reaktivität: | human |
620,00 €
Anti-CD52 (Alemtuzumab Biosimilar In Vivo Antibody (Fc...
Artikelnummer: G-IVMB0228.500
Endotoxin level: < 1.0 EU/mg as determined by the LAL method. Protein function: May play a role in carrying and orienting carbohydrate, as well as having a more specific role. [The UniProt Consortium]
| Schlagworte: | Anti-He5, Anti-CD52, Anti-CDw52, Anti-CDW52, Anti-CAMPATH-1 antigen, Anti-Cambridge pathology 1 antigen, Anti-Epididymal... |
| Anwendung: | CyTOF, ELISA, FA, FC, IHC (frozen), IHC (paraffin), WB |
| Wirt: | Human |
| Spezies-Reaktivität: | human, Rhesus monkey, Cynomolgus monkey |
626,00 €
Anti-VEGF (Bevacizumab Biosimilar In Vivo Antibody)
Artikelnummer: G-IVMB0232.1
Endotoxin level: < 1.0 EU/mg as determined by the LAL method. Protein function: Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1...
| Schlagworte: | Anti-VPF, Anti-VEGF, Anti-VEGFA, Anti-VEGF-A, Anti-Vascular permeability factor, Anti-Vascular endothelial growth factor A |
| Anwendung: | WB, ELISA, FC, IP, Neutr., WB |
| Wirt: | Human |
| Spezies-Reaktivität: | human |
ab 266,00 €
Anti-VEGF (Bevacizumab Biosimilar In Vivo Antibody (Fc...
Artikelnummer: G-IVMB0234.500
Endotoxin level: < 1.0 EU/mg as determined by the LAL method. Protein function: Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1...
| Schlagworte: | Anti-VPF, Anti-VEGF, Anti-VEGFA, Anti-VEGF-A, Anti-Vascular permeability factor, Anti-Vascular endothelial growth factor A |
| Anwendung: | WB, ELISA, FC, IP, Neutr., WB |
| Wirt: | Human |
| Spezies-Reaktivität: | human |
620,00 €
Anti-IL 12/23 (Briakinumab Biosimilar In Vivo Antibody...
Artikelnummer: G-IVMB0237.500
Endotoxin level: < 1.0 EU/mg as determined by the LAL method. Protein function: Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. [The UniProt Consortium]
| Schlagworte: | Anti-NKSF2, Anti-IL12B, Anti-IL-12B, Anti-CLMF p40, Anti-IL-12 subunit p40, Anti-Interleukin-12 subunit beta, Anti-NK cell... |
| Anwendung: | WB, ELISA, FA, FC, IF, IP, Neutr., WB |
| Wirt: | Human |
| Spezies-Reaktivität: | human |
620,00 €