Produkte von RevMAb Biosciences
RevMAb Biosciences, Inc. ist ein Biotechnologie-Unternehmen, das sich auf die Entwicklung rekombinanter, monoklonaler Antikörper unter Einsatz einer neuartigen Methode spezialisiert hat, die ohne Zellfusion und Hybridomgenerierung auskommt. Das Ziel des Unternehmens aus San Francisco, Kalifornien ist die Förderung der allgemeinen Gesundheit durch Unterstützung und Beschleunigung der biomedizinischen Forschung sowie durch das Voranbringen der Krankheitsdiagnostik. RevMAb möchte dies durch die Herstellung bester monoklonaler Antikörper für Kunden in Forschung und Diagnostik erreichen.
Mehr Informationen unter: www.adipogen.com/revmab-biosciences
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Anti-EGFR (human), Rabbit Monoclonal (RM493)
Artikelnummer: REV-31-1385-00-R100
EGFR (Epidermal growth factor receptor, HER1, ErbB1) belongs to the HER/ERbB family of proteins that includes three other receptor tyrosine kinases, ERbB2, ERbB3, ERbB4. EGFR is a transmembrane receptor and binding of its cognate ligands such as EGF (Epidermal Growth Factor) and TGF alpha (Transforming Growth Factor...
| Schlagworte: | Anti-ERBB, EC=2.7.10.1, Anti-Proto-oncogene c-ErbB-1, Anti-Epidermal growth factor receptor, Anti-Receptor... |
| Anwendung: | IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
483,00 €
Anti-ER-alpha (human), Rabbit Monoclonal (RM494)
Artikelnummer: REV-31-1386-00-R100
Estrogen Receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of nuclear receptors. The estrogen receptor is a ligand-activated transcription factor, that when bound to estrogen hormone, induces a conformational change that allows dimerization and binding to estrogen response elements (ERE)...
| Schlagworte: | Anti-ER, Anti-ESR, Anti-ESR1, Anti-ER-alpha, Anti-Estrogen receptor, Anti-Estradiol receptor, Anti-Nuclear receptor... |
| Anwendung: | IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
483,00 €
Anti-CDX2 (human), Rabbit Monoclonal (RM495)
Artikelnummer: REV-31-1387-00-R100
CDX2 is a caudal-type homeobox gene that encodes an intestine-specific transcription factor expressed early in intestinal development and that may be involved in the regulation of proliferation and differentiation of intestinal epithelial cells. CDX2 plays a role in early embryonic development of the intestinal...
| Schlagworte: | Anti-CDX3, Anti-CDX2, Anti-CDX-3, Anti-Homeobox protein CDX-2, Anti-Caudal-type homeobox protein 2 |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
483,00 €
Anti-CD68 (human), Rabbit Monoclonal (RM496)
Artikelnummer: REV-31-1388-00-R100
CD68 [Macrosialin, GP110, SCARD1] is a 110 kDa integral membrane glycoprotein predominantly expressed on the intracellular lysomsomes of monocytes and macrophages and to a lesser extent by dendritic cells and peripheral blood granulocytes. CD68 could play a role in phagocytic activities of tissue macrophages, both...
| Schlagworte: | Anti-CD68, Anti-Gp110, Anti-Macrosialin |
| Anwendung: | IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
483,00 €
Anti-CD45 (human), Rabbit Monoclonal (RM497)
Artikelnummer: REV-31-1389-00-R100
CD45 (LCA, Leukocyte Common Antigen, Protein tyrosine phosphatase, receptor type, C, PTPRC) is a receptor-type protein tyrosine phosphatase (PTP) ubiquitously expressed in all nucleated hematopoietic cells. CD45 is absent on non-hematopoietic cell lines, normal and malignant, non-hematopoietic tissues. CD45...
| Schlagworte: | Anti-L-CA, Anti-CD45, Anti-T200, EC=3.1.3.48, Anti-Leukocyte common antigen, Anti-Receptor-type tyrosine-protein... |
| Anwendung: | IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
483,00 €
Anti-LAIR1 (human), Rabbit Monoclonal (RM498)
Artikelnummer: REV-31-1390-00-R100
LAIR1 functions as an inhibitory receptor that plays a constitutive negative regulatory role on the cytolytic function of natural killer (NK) cells, B-cells and T-cells. Activation by Tyr phosphorylation results in the recruitment and activation of the phosphatases PTPN6 and PTPN11. It also reduces the increase of...
| Schlagworte: | Anti-CD305, Anti-LAIR1, Anti-hLAIR1, Anti-LAIR-1, Anti-Leukocyte-associated immunoglobulin-like receptor 1 |
| Anwendung: | IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
483,00 €
Anti-Galectin-9 (human), Rabbit Monoclonal (RM499)
Artikelnummer: REV-31-1391-00-R100
Galectin-9 (Gal-9), a beta-galactoside-binding protein, primarily plays an immunosuppressive role in the tumor microenvironment, via binding with several cell surface receptors expressed on immune cells. Although Gal-9 was initially identified as a ligand for T-cell immunoglobulin and mucin domain-containing...
| Schlagworte: | Anti-Gal-9, Anti-LGALS9, Anti-Ecalectin, Anti-Galectin-9, Anti-Tumor antigen HOM-HD-21 |
| Anwendung: | IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
483,00 €
Anti-Phospho-DNA-PKcs (Ser2056) (human), Rabbit...
Artikelnummer: REV-31-1392-00-R100
DNA-dependent protein kinase (DNA-PK) is an important factor in the repair of double-stranded breaks in DNA. Cells lacking DNA-PK or in which DNA-PK is inhibited fail to show proper nonhomologous end-joining (NHEJ). DNA-PK is composed of two DNA-binding subunits (Ku70 and Ku86) and one 450 kDa catalytic subunit...
| Schlagworte: | Anti-phospho-p460, Anti-phospho-HYRC, Anti-phospho-DNPK1, Anti-phospho-PRKDC, Anti-phospho-DNA-PKcs, Anti-phospho-DNA-PK... |
| Anwendung: | IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
483,00 €
Anti-CD27 (human), Rabbit Monoclonal (RM501)
Artikelnummer: REV-31-1393-00-R100
CD27 (TNFRSF7) is a member of the TNF-receptor superfamily limited to cells of the lymphoid lineage and exists as both a dimeric glycoprotein on the cell surface and as a soluble protein in serum. As a T and B cell co-stimulatory molecule, the activity of CD27 is governed by its TNF-like ligand CD70 on lymphocytes...
| Schlagworte: | Anti-T14, Anti-CD27, Anti-TNFRSF7, Anti-CD27 antigen, Anti-CD27L receptor, Anti-T-cell activation antigen CD27, Anti-Tumor... |
| Anwendung: | IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
483,00 €
Anti-VISTA, Rabbit Monoclonal (RM503)
Artikelnummer: REV-31-1395-00-R100
Human VISTA is a 55 to 65kDa type I Ig membrane protein with the extracellular domain homologous to PD-L1. VISTA is mainly expressed on hematopoietic tissues (spleen, thymus and bone marrow) and on myeloid cells with lower expression on CD4+ and CD8+ T cells. VISTA is a new negative checkpoint regulator that...
| Schlagworte: | Anti-PP2135, Anti-Sisp-1, Anti-C10orf54, Anti-Platelet receptor Gi24, Anti-V-set immunoregulatory receptor,... |
| Anwendung: | IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
483,00 €
Anti-GCDFP-15 (human), Rabbit Monoclonal (RM504)
Artikelnummer: REV-31-1396-00-R100
Gross cystic disease of the breast is benign premenopausal disorder in which cysts are a predominant pathological lesion. These cysts appear to be formed from excessive apocrine cystic secretions. This fluid is composed of several glycoproteins including a unique 15kDa monomer protein, Gross Cystic Disease Fluid...
| Schlagworte: | Anti-PIP, Anti-SABP, Anti-gp17, Anti-GCDFP15, Anti-GCDFP-15, Anti-Prolactin-induced protein, Anti-Prolactin-inducible... |
| Anwendung: | IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
483,00 €
Anti-DNA-PKcs (human), Rabbit Monoclonal (RM505)
Artikelnummer: REV-31-1397-00-R100
DNA-dependent protein kinase (DNA-PK) is an important factor in the repair of double-stranded breaks in DNA. Cells lacking DNA-PK or in which DNA-PK is inhibited fail to show proper nonhomologous end-joining (NHEJ). DNA-PK is composed of two DNA-binding subunits (Ku70 and Ku86) and one 450 kDa catalytic subunit...
| Schlagworte: | Anti-p460, Anti-HYRC, Anti-DNPK1, Anti-PRKDC, Anti-DNA-PKcs, Anti-DNA-PK catalytic subunit, Anti-DNA-dependent protein... |
| Anwendung: | IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
483,00 €