TMUB2 Protein (His tag) (recombinant human)

Protein Construction: A DNA sequence encoding the human TMUB2 (NP_803190.2) (Tyr37-Ser245) was expressed with an N-terminal polyhistidine tag. Sequence: Tyr37-Ser245. Fusion tag: N-His Endotoxin: < 1.0 EU per µg of the protein as determined by the LAL method. Apparent Molecular Mass: 43 kDa. Protein function: STC2 is a secreted, homodimeric glycoprotein which expressed in a wide variety of tissues. STC2 has an anti-hypocalcemic action on calcium and phosphate homeostasis. It may have autocrine or paracrine functions. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. STC2 has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. It may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis.