STEAP3 protein (GST,His tag), recombinant human

Activity: Testing in progress Protein Construction: A DNA sequence encoding the Human STEAP3 protein (Q658P3) (Met1-Thr258) was expressed with a N-GST&C-His tag. Sequence: Met1-Thr258. Fusion tag: N-GST & C-His Endotoxin: Please contact us for more information. Apparent Molecular Mass: 55 kDa. Protein function: Endosomal ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Participates in erythroid iron homeostasis by reducing Fe(3+) to Fe(2+). Can also reduce of Cu(2+) to Cu(1+), suggesting that it participates in copper h Protein function: Endosomal ferrireductase required for efficient transferrin- dependent iron uptake in erythroid cells. Participates in erythroid iron homeostasis by reducing Fe(3+) to Fe(2+). Can also reduce of Cu(2+) to Cu(1+), suggesting that it participates in copper homeostasis. Uses NADP(+) as acceptor. May play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. Indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCTP. [The UniProt Consortium]