Recombinant Mouse ?-Synuclein/SNCA Protein (His Tag) (RPES3807)

Recombinant Mouse ?-Synuclein/SNCA Protein (His Tag) (RPES3807)
NEU
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
G-RPES3807.10 10 µg - - -

9 - 20 Werktage*

206,00 €
 
Recombinant Mouse ?-Synuclein/SNCA Protein (His Tag) from Assay Genie. Recombinant Mouse... mehr
Produktinformationen "Recombinant Mouse ?-Synuclein/SNCA Protein (His Tag) (RPES3807)"
Recombinant Mouse ?-Synuclein/SNCA Protein (His Tag) from Assay Genie. Recombinant Mouse ?-Synuclein/SNCA Protein (His Tag) is a highly purified recombinant protein produced in E.coli and for the use in functional assays from Assay Genie.. Protein function: Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores. Mechanistically, acts by increasing local Ca(2+) release from microdomains which is essential for the enhancement of ATP-induced exocytosis. Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs (Soluble NSF Attachment Protein REceptors) at presynaptic plasma membrane in conjunction with cysteine string protein-alpha/DNAJC5 (PubMed:20798282, PubMed:25246573). This chaperone activity is important to sustain normal SNARE-complex assembly during aging. Plays also a role in the regulation of the dopamine neurotransmission by associating with the dopamine transporter (DAT1) and thereby modulating its activity. [The UniProt Consortium]
Schlagworte: Syn, Snca, NACP, Alpha-synuclein, Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor
Hersteller: Assay Genie
Hersteller-Nr: RPES3807

Eigenschaften

Konjugat: No
Exprimiert in: E.coli
Ursprungsart: Mouse
Format: Highly Purified

Datenbank Information

KEGG ID : K04528 | Passende Produkte
UniProt ID : O55042 | Passende Produkte

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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