Recombinant Human Syntaxin-7/STX7 (N-6His)

Source: Human Cells. MW :28kD. Recombinant Human Syntaxin-7 is produced by our Mammalian expression system and the target gene encoding Ser2-Leu238 is expressed with a 6His tag at the N-terminus. Syntaxin 7 (STX7) is a member of a family of membrane-trafficking proteins named as soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs), and mediates the endocytic trafficking from early endosomes to late endosomes and lysosomes. Syntaxin-7 has been shown to be present in both late endosomes and lysosomes, and to be required for both homotypic late endosome fusion and heterotypic fusion with lysosomes. STX7 has been shown to interact with STX8, VPS18, Vesicle-associated membrane protein 8 and VPS11. Protein function: May be involved in protein trafficking from the plasma membrane to the early endosome (EE) as well as in homotypic fusion of endocytic organelles. Mediates the endocytic trafficking from early endosomes to late endosomes and lysosomes. [The UniProt Consortium]