Recombinant Human NUDT5/ADP-sugar Pyrophosphatase Protein (His Tag) (RPES4610)

Recombinant Human NUDT5/ADP-sugar Pyrophosphatase Protein (His Tag) (RPES4610)
NEU
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
G-RPES4610.10 10 µg - - -

9 - 20 Werktage*

524,00 €
 
Recombinant Human NUDT5/ADP-sugar Pyrophosphatase Protein (His Tag) from Assay Genie. Recombinant... mehr
Produktinformationen "Recombinant Human NUDT5/ADP-sugar Pyrophosphatase Protein (His Tag) (RPES4610)"
Recombinant Human NUDT5/ADP-sugar Pyrophosphatase Protein (His Tag) from Assay Genie. Recombinant Human NUDT5/ADP-sugar Pyrophosphatase Protein (His Tag) is a highly purified recombinant protein produced in E.coli and for the use in functional assays from Assay Genie.. Protein function: Enzyme that can either act as an ADP-sugar pyrophosphatase in absence of diphosphate or catalyze the synthesis of ATP in presence of diphosphate (PubMed:27257257). In absence of diphosphate, hydrolyzes with similar activities various modified nucleoside diphosphates such as ADP-ribose, ADP-mannose, ADP-glucose, 8-oxo-GDP and 8-oxo-dGDP (PubMed:10567213, PubMed:10722730, PubMed:19699693, PubMed:21389046, PubMed:17052728). Can also hydrolyze other nucleotide sugars with low activity (PubMed:19699693, PubMed:21389046). In presence of diphosphate, mediates the synthesis of ATP in the nucleus by catalyzing the conversion of ADP-ribose to ATP and ribose 5-phosphate. Nuclear ATP synthesis takes place when dephosphorylated at Thr-45 (PubMed:27257257). Nuclear ATP generation is required for extensive chromatin remodeling events that are energy-consuming (PubMed:27257257). Does not play a role in U8 snoRNA decapping activity. Binds U8 snoRNA. [The UniProt Consortium]
Schlagworte: NUDT5, YSA1H, hNUDT5, Nudix motif 5, 8-oxo-dGDP phosphatase, ADP-sugar pyrophosphatase, Nuclear ATP-synthesis protein NUDIX5, Nucleoside diphosphate-linked moiety X motif 5
Hersteller: Assay Genie
Hersteller-Nr: RPES4610

Eigenschaften

Konjugat: No
Exprimiert in: E.coli
Ursprungsart: Human
Format: Highly Purified

Datenbank Information

KEGG ID : K13987 | Passende Produkte
UniProt ID : Q9UKK9 | Passende Produkte

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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