Recombinant Human Carboxylesterase 1/CES1 Protein (His Tag) (RPES4375)

Recombinant Human Carboxylesterase 1/CES1 Protein (His Tag) (RPES4375)
NEU
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
G-RPES4375.10 10 µg - - -

9 - 20 Werktage*

379,00 €
 
Recombinant Human Carboxylesterase 1/CES1 Protein (His Tag) from Assay Genie. Recombinant Human... mehr
Produktinformationen "Recombinant Human Carboxylesterase 1/CES1 Protein (His Tag) (RPES4375)"
Recombinant Human Carboxylesterase 1/CES1 Protein (His Tag) from Assay Genie. Recombinant Human Carboxylesterase 1/CES1 Protein (His Tag) is a highly purified recombinant protein produced in Human Cells and for the use in functional assays from Assay Genie.. Protein function: Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs (PubMed:7980644, PubMed:9169443, PubMed:9490062, PubMed:18762277). Hydrolyzes aromatic and aliphatic esters, but has no catalytic activity toward amides or a fatty acyl-CoA ester (PubMed:7980644, PubMed:9169443, PubMed:9490062, PubMed:18762277). Hydrolyzes the methyl ester group of cocaine to form benzoylecgonine (PubMed:7980644). Catalyzes the transesterification of cocaine to form cocaethylene (PubMed:7980644). Displays fatty acid ethyl ester synthase activity, catalyzing the ethyl esterification of oleic acid to ethyloleate (PubMed:7980644). Converts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes of 2-arachidonoylglycerol and prostaglandins (PubMed:21049984). Hydrolyzes cellular cholesteryl esters to free cholesterols and promotes reverse cholesterol transport (RCT) by facilitating both the initial and final steps in the process (PubMed:18762277, PubMed:16024911, PubMed:11015575, PubMed:16971496). First of all, allows free cholesterol efflux from macrophages to extracellular cholesterol acceptors and secondly, releases free cholesterol from lipoprotein-delivered cholesteryl esters in the liver for bile acid synthesis or direct secretion into the bile (PubMed:18762277, PubMed:18599737, PubMed:16971496). [The UniProt Consortium]
Schlagworte: REH, TGH, CEH, CE-1, HMSE, ACAT, CES2, hCE-1, Egasyn, Serine esterase 1, Carboxylesterase 1, Retinyl ester hydrolase, Cocaine carboxylesterase, Liver carboxylesterase 1, Triacylglycerol hydrolase, Brain carboxylesterase hBr1, Cholesteryl ester hydrolase
Hersteller: Assay Genie
Hersteller-Nr: RPES4375

Eigenschaften

Konjugat: No
Exprimiert in: Human cells
Ursprungsart: Human
Format: Highly Purified

Datenbank Information

KEGG ID : K01044 | Passende Produkte
UniProt ID : P23141 | Passende Produkte

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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