MTPN, aa1-118, Recombinant, Human (FLJ31098, FLJ99857, GCDP, Myotrophin, MYOTROPHIN, Protein V-1, V-

MTPN (myotrophin), an ankyrin repeat protein, is stimulates protein synthesis and cardiomyocyte growth to initiate cardiac hypertrophy by activating the NF-kappaB signaling cascade. This protein plays a potential role in cerebellar morphogenesis and may function in differentiation of cerebellar neurons, particularly of granule cells. Elevated levels of MTPN are expressed in human dilated cardiomyopathic and ischemic hearts. Source: Recombinant corresponding to aa1-118 of human MTPN 6x his tagged, expressed in E.coli. AA Sequences: MGSSHHHHHH SSGLVPRGSH MCDKEFMWAL KNGDLDEVKD YVAKGEDVNR TLEGGRKPLH YAADCGQLEI LEFLLLKGAD INAPDKHHIT PLLSAVYEGH VSCVKLLLSK GADKTVKGPDGLTAFEATDN QAIKALLQ, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.