KLK7 protein (His tag), recombinant human

Activity: Testing in progress Protein Construction: A DNA sequence encoding the Human KLK7 protein (P49862) (Glu23-Arg253) was expressed with a N-His . Sequence: Glu 23-Arg 253. Fusion tag: N-His Endotoxin: Please contact us for more information. Apparent Molecular Mass: 31 kDa. Protein function: Human Kallikrein 7 is a member of the tissue kallikrein family of extracellular serine proteases that is made up of 15 members. It is predominantly expressed in the skin. A major physiological function of Kallikrein 7 is to regulate the desquamation proce Protein function: May catalyze the degradation of intercellular cohesive structures in the cornified layer of the skin in the continuous shedding of cells from the skin surface. Specific for amino acid residues with aromatic side chains in the P1 position. Cleaves insulin A chain at '14-Tyr-, -Gln-15' and insulin B chain at '6-Leu-, -Cys-7', '16-Tyr-, -Leu-17', '25-Phe-, -Tyr-26' and '26-Tyr-, -Thr-27'. Could play a role in the activation of precursors to inflammatory cytokines. [The UniProt Consortium]