Human LTBR, Fc fusion HiP(TM)

Human secreted lymphotoxin beta receptor (LTBR)-Fc fusion protein, also known as, Tumor Necrosis Factor C Receptor (TNFCR), and CD18, GenBank Accession No. NM_002342, a.a 28-219, expressed in a HEK293 cell expression system. MW = 48 kDa (monomer). This protein runs at a higher apparent M.W. by SDS-PAGE due to glycosylation. Protein function: Receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. Promotes apoptosis via TRAF3 and TRAF5. May play a role in the development of lymphoid organs. [The UniProt Consortium]