GADD45A protein (His tag), recombinant human

Activity: Testing in progress Protein Construction: A DNA sequence encoding the Human GADD45A protein (P24522 ) (1M-165R) was expressed with N-His tag. Sequence: Met 1-Arg 165. Fusion tag: N-His Endotoxin: Please contact us for more information. Apparent Molecular Mass: 23 kDa. Protein function: GADD45 alpha (Growth arrest and DNA damage-inducible protein 45 alpha) is a 19 kDa member of the GADD45 family of proteins. It is ubiquitously expressed, and induced by DNA damage. Upon induction, GADD45 alpha binds to PCNA, stimulates DNA excision repair Protein function: In T-cells, functions as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity. Might affect PCNA interaction with some CDK (cell division protein kinase) complexes, stimulates DNA excision repair in vitro and inhibits entry of cells into S phase. [The UniProt Consortium]