cerevisiae TIM16 Protein (recombinant s.)

Protein Construction: Recombinant S. cerevisiae TIM16 is produced by our E.coli expression system and the target gene encoding Thr54-Ala119 is expressed. Sequence: Thr54-Ala119. Endotoxin: < 1.0 EU per µg as determined by the LAL method. Apparent Molecular Mass: 11 kDa. Protein function: Mitochondrial import inner membrane translocase subunit TIM16 (TIM16) is an ssential component of the PAM complex. PAM complex is required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, TIM16 is required to regulate activity of mtHSP70 (SSC1) via its interaction with PAM18/TIM14. TIM16 may act by positioning PAM18/TIM14 in juxtaposition to mtHSP70 at the translocon to maximize ATPase stimulation. Protein function: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, it is required to regulate activity of mtHSP70 (SSC1) via its interaction with PAM18/TIM14. May act by positioning PAM18/TIM14 in juxtaposition to mtHSP70 at the translocon to maximize ATPase stimulation. [The UniProt Consortium]