CEL-BSA

Advanced glycation end products (AGEs) are formed from the nonenzymatic reaction of amino groups with reducing sugars. AGEs have been implicated in diseases, such as diabetes mellitus, non-diabetic nephropathy, macrovascular disease, Alzheimer's disease, cataract, and ageing. AGE receptors, such as the receptor for AGE (RAGE), mediate biological responses to AGEs, including endocytic uptake and degradation and induction of cytokines and growth factors. CEL-BSA was produced by incubating BSA with sodium pyruvate and cyanoborohydride.Synonyms: Nepsilon-(1-Carboxyethyl)-L-lysine-Bovine Serum Albumin, Nepsilon-(1-Carboxyethyl)-L-lysine-BSA. Source: Albumin isolated from bovine plasma and modified by carboxyethylation. MW: 69.3 kDa. Formulation: (Request formulation change), Lyophilized from a solution in PBS, pH 7.4, at 0.2 mg per vial. Reconstitution with 200 µl of water will yield 1 mg/ml solution in 1X PBS.