Arginase (EC 3.5.3.1), Homo sapiens liver

Arginase (L-arginine amidinohydrolase, EC 3.5.3.1) is a manganese-containing enzyme that catalyses the hydrolysis of L-arginine to L-ornithine and urea. It is abundantly present in the liver of ureotelic animals, where catalyses the final step in the urea cycle. The deficiency, known as hyperargininemia or arginemia, is hereditary and autosomal recessive. It is characterized by lowered activity of arginase in hepatic cells. Symptoms of the disorder include neurological impairment, dementia, retardation of growth and hyperammonemia. NZYtech`s arginase comprises the recombinant human liver enzyme expressed and purified from a modified Escherichia coli strain. The enzyme is provided in 2.5 M lithium sulphate. Temperature and pH optimum/stability: 10-11 and 25-40 °C, respectively. Activity: 1950 U/ml. Shipping Conditions: Room Temperature. Storage Conditions: 2 °C to 8 °C. Features: >95% pure (SDS-PAGE). ARG1, Arginase-1, Type I arginase, Liver-type arginase