Antithrombin-III/AT3 protein (His tag), recombinant human

Activity: Testing in progress Protein Construction: A DNA sequence encoding the Human AT- III protein (P01008) (1-464) was expressed with a C-His. Sequence: Met 1-Lys 464. Fusion tag: C-His Endotoxin: Please contact us for more information. Apparent Molecular Mass: 60 kDa. Protein function: SerpinC1, also known as antithrombin III (AT III), is a member of the serpin superfamily of serine protease inhibitors, and has been found to be a marker for disseminated intravascular coagulation (DIC) and to be of prognostic significance in septic patie Protein function: Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade (PubMed:15853774, PubMed:15140129). AT-III inhibits thrombin, matriptase-3/TMPRSS7, as well as factors IXa, Xa and XIa (PubMed:15140129). Its inhibitory activity is greatly enhanced in the presence of heparin. [The UniProt Consortium]