Aldehyde Dehydrogenase 1-A2/ALDH1A2 Protein(N-6His) (recombinant human)

Aldehyde Dehydrogenase 1-A2/ALDH1A2 Protein(N-6His) (recombinant human)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
E-PKSH032053.10 10 µg - -

7 - 16 Werktage*

287,00 €
E-PKSH032053.50 50 µg - -

7 - 16 Werktage*

488,00 €
 
Protein Construction: Recombinant Human Aldehyde dehydrogenase family 1 member A2 is produced by... mehr
Produktinformationen "Aldehyde Dehydrogenase 1-A2/ALDH1A2 Protein(N-6His) (recombinant human)"
Protein Construction: Recombinant Human Aldehyde dehydrogenase family 1 member A2 is produced by our E.coli expression system and the target gene encoding Met1-Ser518 is expressed with a 6His tag at the N-terminus. Sequence: Met 1-Ser518. Fusion tag: N-6His Endotoxin: < 1.0 EU per µg as determined by the LAL method. Apparent Molecular Mass: 50-65 kDa. Protein function: Aldehyde dehydrogenase 1 family member A2 (ALDH1A2), also known as retinaldehyde dehydrogenase 2 (RALDH2), belongs to the aldehyde dehydrogenase family which contains two members, the ALDH1 s (ALDH1A1, ALDH1A2 and ALDH1A3) and the 9-cis retinaldehyde dehydrogenase ALDH8 s. ALDH1A2 is key enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. RA is a paracrine hormone signaling molecule that functions in developing and adult tissues. ALDH1A2 was also found to regulate normal and tumor cell growth and differentiation. Several studies showed that ALDH1A2 expression is increased after the appearance of AraC resistance in clinical cases which means this protein is effective in AraC resistance. Protein function: Recognizes as substrates free retinal and cellular retinol-binding protein-bound retinal. Does metabolize octanal and decanal but does not metabolize citral, benzaldehyde, acetaldehyde and propanal efficiently. [The UniProt Consortium]
Schlagworte: RalDH2, RALDH2, RALDH 2, ALDH1A2, RALDH(II), EC=1.2.1.36, Retinal dehydrogenase 2, Aldehyde dehydrogenase family 1 member A2, Retinaldehyde-specific dehydrogenase type 2, Recombinant Human Aldehyde Dehydrogenase 1-A2/ALDH1A2 Protein(N-6His)
Hersteller: Elabscience
Hersteller-Nr: E-PKSH032053

Eigenschaften

Konjugat: No
Exprimiert in: E.coli
Ursprungsart: Human
MW: 58.2 kD
Format: Solution

Handhabung & Sicherheit

Lagerung: -80°C
Versand: -20°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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